Details
| Original language | English |
|---|---|
| Pages (from-to) | 327-337 |
| Number of pages | 11 |
| Journal | Biomedical Engineering Letters |
| Volume | 9 |
| Issue number | 3 |
| Early online date | 25 Jul 2019 |
| Publication status | Published - 1 Aug 2019 |
Abstract
Monte Carlo (MC) simulation for light propagation in scattering and absorbing media is the gold standard for studying the interaction of light with biological tissue and has been used for years in a wide variety of cases. The interaction of photons with the medium is simulated based on its optical properties and the original approximation of the scattering phase function. Over the past decade, with the new measurement geometries and recording techniques invented also the corresponding sophisticated methods for the description of the underlying light–tissue interaction taking into account realistic parameters and settings were developed. Applications, such as multiple scattering, optogenetics, optical coherence tomography, Raman spectroscopy, polarimetry and Mueller matrix measurement have emerged and are still constantly improved. Here, we review the advances and recent applications of MC simulation for the active field of the life sciences and the medicine pointing out the new insights enabled by the theoretical concepts.
Keywords
- Biotissue, Light-matter interaction, Monte Carlo simulation, Scattering and absorbing media
ASJC Scopus subject areas
- Engineering(all)
- Biomedical Engineering
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In: Biomedical Engineering Letters, Vol. 9, No. 3, 01.08.2019, p. 327-337.
Research output: Contribution to journal › Review article › Research › peer review
}
TY - JOUR
T1 - Advances in the simulation of light–tissue interactions in biomedical engineering
AU - Krasnikov, Ilya
AU - Seteikin, Alexey
AU - Roth, Bernhard
N1 - Funding Information: The State task of the Ministry of Education and Science of the Russian Federation (Project # 3.5022.3017/8.9). B.R. acknowledges funding by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy within the Cluster of Excellence PhoenixD (EXC 2122).
PY - 2019/8/1
Y1 - 2019/8/1
N2 - Monte Carlo (MC) simulation for light propagation in scattering and absorbing media is the gold standard for studying the interaction of light with biological tissue and has been used for years in a wide variety of cases. The interaction of photons with the medium is simulated based on its optical properties and the original approximation of the scattering phase function. Over the past decade, with the new measurement geometries and recording techniques invented also the corresponding sophisticated methods for the description of the underlying light–tissue interaction taking into account realistic parameters and settings were developed. Applications, such as multiple scattering, optogenetics, optical coherence tomography, Raman spectroscopy, polarimetry and Mueller matrix measurement have emerged and are still constantly improved. Here, we review the advances and recent applications of MC simulation for the active field of the life sciences and the medicine pointing out the new insights enabled by the theoretical concepts.
AB - Monte Carlo (MC) simulation for light propagation in scattering and absorbing media is the gold standard for studying the interaction of light with biological tissue and has been used for years in a wide variety of cases. The interaction of photons with the medium is simulated based on its optical properties and the original approximation of the scattering phase function. Over the past decade, with the new measurement geometries and recording techniques invented also the corresponding sophisticated methods for the description of the underlying light–tissue interaction taking into account realistic parameters and settings were developed. Applications, such as multiple scattering, optogenetics, optical coherence tomography, Raman spectroscopy, polarimetry and Mueller matrix measurement have emerged and are still constantly improved. Here, we review the advances and recent applications of MC simulation for the active field of the life sciences and the medicine pointing out the new insights enabled by the theoretical concepts.
KW - Biotissue
KW - Light-matter interaction
KW - Monte Carlo simulation
KW - Scattering and absorbing media
UR - http://www.scopus.com/inward/record.url?scp=85069745332&partnerID=8YFLogxK
U2 - 10.1007/s13534-019-00123-x
DO - 10.1007/s13534-019-00123-x
M3 - Review article
C2 - 31456892
AN - SCOPUS:85069745332
VL - 9
SP - 327
EP - 337
JO - Biomedical Engineering Letters
JF - Biomedical Engineering Letters
SN - 2093-9868
IS - 3
ER -