Details
| Original language | English |
|---|---|
| Title of host publication | Biophotonics in Exercise Science, Sports Medicine, Health Monitoring Technologies, and Wearables VI |
| Editors | Babak Shadgan, Amir H. Gandjbakhche |
| Publisher | SPIE |
| Number of pages | 13 |
| ISBN (electronic) | 9781510683747 |
| Publication status | Published - 20 Mar 2025 |
| Event | SPIE Photonics West BiOS 2025 - San Francisco, United States Duration: 25 Jan 2025 → 31 Jan 2025 |
Publication series
| Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
|---|---|
| Volume | 13313 |
| ISSN (Print) | 1605-7422 |
Abstract
We have developed a portable optical detector, known as the Transilluminated Quantum Dot (TIQD) imager and a highly accurate biochip for minimally invasive training load monitoring in sports, to track athlete’s stress and recovery cycles. The goal was to simultaneously detect critical stress markers in blood and saliva. In the procedure so far, blood samples are collected on-site, frozen, and transported to laboratories for conventional ELISA testing. This process is time-consuming and is prone to sample loss. Portable monitoring could provide faster and more cost-effective testing. The miniaturized optical detector and biochip described here represents a step towards this goal and might, in addition, enable rapid point-of-care medical diagnostics in the future. The system can be further developed and integrated with mobile phones to realize a low-cost, low-footprint, and yet reliable rapid tests for biomolecules relevant for self-monitoring and point-of-care (POC) diagnostics.
Keywords
- biochip, biotinylated antibodies, Hsp70, Hsp90, multiplexed detection, PMT-scanner, POC tests, portable optical detector, quantum dots, stress biomarkers, TIQD imager
ASJC Scopus subject areas
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Physics and Astronomy(all)
- Atomic and Molecular Physics, and Optics
- Materials Science(all)
- Biomaterials
- Medicine(all)
- Radiology Nuclear Medicine and imaging
Cite this
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Biophotonics in Exercise Science, Sports Medicine, Health Monitoring Technologies, and Wearables VI. ed. / Babak Shadgan; Amir H. Gandjbakhche. SPIE, 2025. 133130A (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 13313).
Research output: Chapter in book/report/conference proceeding › Conference contribution › Research › peer review
}
TY - GEN
T1 - Stress biomarker test for athletes with portable optical detector and functionalized quantum dots
AU - Kishore, Anusha
AU - Varughese, Arun Mathew
AU - Roth, Bernhard
AU - Zeilinger, Carsten
N1 - Publisher Copyright: © 2025 SPIE.
PY - 2025/3/20
Y1 - 2025/3/20
N2 - We have developed a portable optical detector, known as the Transilluminated Quantum Dot (TIQD) imager and a highly accurate biochip for minimally invasive training load monitoring in sports, to track athlete’s stress and recovery cycles. The goal was to simultaneously detect critical stress markers in blood and saliva. In the procedure so far, blood samples are collected on-site, frozen, and transported to laboratories for conventional ELISA testing. This process is time-consuming and is prone to sample loss. Portable monitoring could provide faster and more cost-effective testing. The miniaturized optical detector and biochip described here represents a step towards this goal and might, in addition, enable rapid point-of-care medical diagnostics in the future. The system can be further developed and integrated with mobile phones to realize a low-cost, low-footprint, and yet reliable rapid tests for biomolecules relevant for self-monitoring and point-of-care (POC) diagnostics.
AB - We have developed a portable optical detector, known as the Transilluminated Quantum Dot (TIQD) imager and a highly accurate biochip for minimally invasive training load monitoring in sports, to track athlete’s stress and recovery cycles. The goal was to simultaneously detect critical stress markers in blood and saliva. In the procedure so far, blood samples are collected on-site, frozen, and transported to laboratories for conventional ELISA testing. This process is time-consuming and is prone to sample loss. Portable monitoring could provide faster and more cost-effective testing. The miniaturized optical detector and biochip described here represents a step towards this goal and might, in addition, enable rapid point-of-care medical diagnostics in the future. The system can be further developed and integrated with mobile phones to realize a low-cost, low-footprint, and yet reliable rapid tests for biomolecules relevant for self-monitoring and point-of-care (POC) diagnostics.
KW - biochip
KW - biotinylated antibodies
KW - Hsp70
KW - Hsp90
KW - multiplexed detection
KW - PMT-scanner
KW - POC tests
KW - portable optical detector
KW - quantum dots
KW - stress biomarkers
KW - TIQD imager
UR - http://www.scopus.com/inward/record.url?scp=105004341004&partnerID=8YFLogxK
U2 - 10.1117/12.3040893
DO - 10.1117/12.3040893
M3 - Conference contribution
AN - SCOPUS:105004341004
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Biophotonics in Exercise Science, Sports Medicine, Health Monitoring Technologies, and Wearables VI
A2 - Shadgan, Babak
A2 - Gandjbakhche, Amir H.
PB - SPIE
T2 - SPIE Photonics West BiOS 2025
Y2 - 25 January 2025 through 31 January 2025
ER -