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  1. 2023
  2. Published

    Development of novel PEX5-PEX14 protein-protein interaction (PPI) inhibitors based on an oxopiperazine template

    Marciniak, M., Mróz, P., Napolitano, V., Kalel, V. C., Fino, R., Pykacz, E., Schliebs, W., Plettenburg, O., Erdmann, R., Sattler, M., Popowicz, G. M. & Dawidowski, M., 5 Oct 2023, In: European Journal of Medicinal Chemistry. 258, 115587.

    Research output: Contribution to journal › Article › Research › peer review

  3. Published

    Development of a peptide drug restoring AMPK and adipose tissue functionality in cancer cachexia

    Ji, H., Englmaier, F., Morigny, P., Giroud, M., Gräsle, P., Brings, S., Szendrödi, J., Berriel Diaz, M., Plettenburg, O., Herzig, S. & Rohm, M., 2 Aug 2023, In: Molecular therapy. 31, 8, p. 2408-2421 14 p.

    Research output: Contribution to journal › Article › Research › peer review

  4. Published

    A Chemical Chaperone Restores Connexin 26 Mutant Activity

    Wang, D., Wang, H., Fan, L., Ludwig, T., Wegner, A., Stahl, F., Harre, J., Warnecke, A. & Zeilinger, C., 14 Jul 2023, In: ACS Pharmacology & Translational Science. 6, 7, p. 997–1005 9 p.

    Research output: Contribution to journal › Article › Research › peer review

  5. 2022
  6. Published

    Identification of structurally re-engineered rocaglates as inhibitors against hepatitis E virus replication

    Praditya, D. F., Klöhn, M., Brüggemann, Y., Brown, L. E., Porco, J. A., Zhang, W., Kinast, V., Kirschning, A., Vondran, F. W. R., Todt, D. & Steinmann, E., Aug 2022, In: Antiviral Research. 204, 105359.

    Research output: Contribution to journal › Article › Research › peer review

  7. Published

    Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses

    Napolitano, V., Dabrowska, A., Schorpp, K., Mourão, A., Barreto-Duran, E., Benedyk, M., Botwina, P., Brandner, S., Bostock, M., Chykunova, Y., Czarna, A., Dubin, G., Fröhlich, T., Hölscher, M., Jedrysik, M., Matsuda, A., Owczarek, K., Pachota, M., Plettenburg, O., Potempa, J., Rothenaigner, I., Schlauderer, F., Slysz, K., Szczepanski, A., Greve-Isdahl Mohn, K., Blomberg, B., Sattler, M., Hadian, K., Popowicz, G. M. & Pyrc, K., 19 May 2022, In: Cell Chemical Biology. 29, 5, p. 774-784

    Research output: Contribution to journal › Article › Research › peer review

  8. Published

    A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells

    Yin, H., Karayel, O., Chao, Y. Y., Seeholzer, T., Hamp, I., Plettenburg, O., Gehring, T., Zielinski, C., Mann, M. & Krappmann, D., Feb 2022, In: Cellular and Molecular Life Sciences. 79, 2, 112.

    Research output: Contribution to journal › Article › Research › peer review

  9. 2021

  10. Divergent synthesis and biological evaluation of 2-(trifluoromethyl)pyridines as virulence-attenuating inverse agonists targeting PqsR

    Schütz, C., Hodzic, A., Hamed, M., Abdelsamie, A. S., Kany, A. M., Bauer, M., Röhrig, T., Schmelz, S., Scrima, A., Blankenfeldt, W. & Empting, M., 15 Dec 2021, In: European Journal of Medicinal Chemistry. 226, 113797.

    Research output: Contribution to journal › Article › Research › peer review

  11. Structure-Activity Relationship and Mode-Of-Action Studies Highlight 1-(4-Biphenylylmethyl)-1H-imidazole-Derived Small Molecules as Potent CYP121 Inhibitors

    Walter, I., Adam, S., Gentilini, M. V., Kany, A. M., Brengel, C., Thomann, A., Sparwasser, T., Köhnke, J. & Hartmann, R. W., 16 Sept 2021, In: CHEMMEDCHEM. 16, 18, p. 2786-2801 16 p.

    Research output: Contribution to journal › Article › Research › peer review

  12. Published

    Improving Risk Assessment in Clinical Trials: Toward a Systematic Risk-Based Monitoring Approach

    Fneish, F., Schaarschmidt, F. & Fortwengel, G., 28 Aug 2021, In: Current Therapeutic Research - Clinical and Experimental. 95, 100643.

    Research output: Contribution to journal › Article › Research › peer review

  13. Published

    Mechano-chemo-biological computational models for arteries in health, disease and healing: From tissue remodelling to drug-eluting devices

    Marino, M., Vairo, G. & Wriggers, P., May 2021, In: Current Pharmaceutical Design. 27, 16, p. 1904-1917 14 p.

    Research output: Contribution to journal › Review article › Research › peer review

  14. Published

    Modeling of Symbiotic Bacterial Biofilm Growth with an Example of the Streptococcus–Veillonella sp. System

    Feng, D., Neuweiler, I., Nogueira, R. & Nackenhorst, U., 24 Mar 2021, In: Bulletin of mathematical biology. 83, 5, 48.

    Research output: Contribution to journal › Article › Research › peer review

  15. Published

    A patent review of MALT1 inhibitors (2013-present)

    Hamp, I., O’Neill, T. J., Plettenburg, O. & Krappmann, D., 2021, In: Expert Opinion on Therapeutic Patents. 31, 12, p. 1079-1096 18 p.

    Research output: Contribution to journal › Review article › Research › peer review

  16. 2020

  17. INSPIRE: A European training network to foster research and training in cardiovascular safety pharmacology

    Guns, P. J. D., Guth, B. D., Braam, S., Kosmidis, G., Matsa, E., Delaunois, A., Gryshkova, V., Bernasconi, S., Knot, H. J., Shemesh, Y., Chen, A., Markert, M., Fernández, M. A., Lombardi, D., Grandmont, C., Cillero-Pastor, B., Heeren, R. M. A., Martinet, W., Woolard, J., Skinner, M., Segers, V. F. M., Franssen, C., Van Craenenbroeck, E. M., Volders, P. G. A., Pauwelyn, T., Braeken, D., Yanez, P., Correll, K., Yang, X., Prior, H., Kismihók, G., De Meyer, G. R. Y. & Valentin, J. P., Sept 2020, In: Journal of Pharmacological and Toxicological Methods. 105, 106889.

    Research output: Contribution to journal › Article › Research › peer review

  18. Published

    Provenance effect on bioactive phytochemicals and nutritional and health benefits of the desert date Balanites aegyptiaca

    Khamis, G., Saleh, A. M., Habeeb, T. H., Hozzein, W. N., Wadaan, M. A. M., Papenbrock, J. & AbdElgawad, H., 10 Jun 2020, In: Journal of food biochemistry. 44, 6, e13229.

    Research output: Contribution to journal › Article › Research › peer review

  19. Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry

    Blockus, S., Sake, S. M., Wetzke, M., Grethe, C., Graalmann, T., Pils, M., Le Goffic, R., Galloux, M., Prochnow, H., Rox, K., Hüttel, S., Rupcic, Z., Wiegmann, B., Dijkman, R., Rameix-Welti, M. A., Eléouët, J. F., Duprex, W. P., Thiel, V., Hansen, G., Brönstrup, M., Haid, S. & Pietschmann, T., May 2020, In: Antiviral Research. 177, 104774.

    Research output: Contribution to journal › Article › Research › peer review

  20. 2019
  21. Published

    Stability and Biological Activity of E. coli Derived Soluble and Precipitated Bone Morphogenetic Protein-2

    Quaas, B., Burmeister, L., Li, Z., Satalov, A., Behrens, P., Hoffmann, A. & Rinas, U., 20 Nov 2019, In: Pharmaceutical research. 36, 12, 184.

    Research output: Contribution to journal › Article › Research › peer review

  22. Published

    Highly variable pharmacokinetics of tyramine in humans and polymorphisms in OCT1, CYP2D6, and MAO-A

    Rafehi, M., Faltraco, F., Matthaei, J., Prukop, T., Jensen, O., Grytzmann, A., Blome, F. G., Berger, R. G., Krings, U., Vormfelde, S. V., Tzvetkov, M. V. & Brockmöller, J., 30 Oct 2019, In: Frontiers in pharmacology. 10, OCT, p. 1297 1297.

    Research output: Contribution to journal › Article › Research › peer review

  23. Published

    Claims Data Analysis on the Dispensing of Tricyclic Antidepressants Among Patients with Dementia in Germany

    Hessmann, P., Zeidler, J., Stahmeyer, J., Eberhard, S., Vogelgsang, J., Abdel-Hamid, M., Wolff-Menzler, C., Wiltfang, J. & Kis, B., Jul 2019, In: Frontiers in Pharmacology. 10, 841.

    Research output: Contribution to journal › Article › Research › peer review

  24. Published

    Externally Induced Drug Release Systems with Magnetic Nanoparticle Carriers: An Emerging Field in Nanomedicine

    Norris, M. D., Seidel, K. & Kirschning, A., 10 Jan 2019, In: Advanced Therapeutics. 2, 1, 12 p., 1800092.

    Research output: Contribution to journal › Article › Research

  25. 3D organ models: Revolution in pharmacological research?

    Weinhart, M., Hocke, A., Hippenstiel, S., Kurreck, J. & Hedtrich, S., Jan 2019, In: Pharmacological Research. 139, p. 446-451 6 p.

    Research output: Contribution to journal › Article › Research › peer review

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