Details
| Original language | English |
|---|---|
| Pages (from-to) | 1264-1273 |
| Number of pages | 10 |
| Journal | Journal of Biomaterials Applications |
| Volume | 28 |
| Issue number | 8 |
| Early online date | 8 Oct 2013 |
| Publication status | Published - Apr 2014 |
Abstract
In this in vitro study, magnesium plates of ZEK100 and MgCa0.8 alloy similar to common titanium alloy osteosynthesis plates were investigated as degradable biomedical materials with a focus on primary stability. Immersion tests were performed in Hank's Balanced Salt Solution at 37. The bending strength of the samples was determined using the four-point bending test according to ISO 9585:1990. The initial strength of the noncorroded ZEK100 plate was 11% greater than that of the MgCa0.8 plate; both were approximately 65% weaker than a titanium plate. The bending strength was determined after 48 and 96 h of immersion in Hank's Balanced Salt Solution; both magnesium alloys decreased by approximately 7% after immersion for 96 h. The degradation rate and the Mg2+ release of ZEK100 were lower than those of MgCa0.8. Strong pitting and filiform corrosion were observed in the MgCa0.8 samples after 96 h of immersion. The surface of the ZEK100 plates exhibited only small areas of filiform corrosion. The results of this in vitro study indicate that the ZEK100 alloy may be more suitable for biomedical applications.
Keywords
- corrosion, implants, In vitro, magnesium, orthopedic
ASJC Scopus subject areas
- Materials Science(all)
- Biomaterials
- Engineering(all)
- Biomedical Engineering
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In: Journal of Biomaterials Applications, Vol. 28, No. 8, 04.2014, p. 1264-1273.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Comparative in vitro study and biomechanical testing of two different magnesium alloys
AU - Weizbauer, Andreas
AU - Modrejewski, Christian
AU - Behrens, Sabine
AU - Klein, Helmut
AU - Helmecke, Patrick
AU - Seitz, Jan Marten
AU - Windhagen, Henning
AU - Möhwald, Kai
AU - Reifenrath, Janin
AU - Waizy, Hazibullah
N1 - Funding Information: The authors gratefully acknowledge the financial support provided by the German Research Society (DFG) within the collaborative research project (SFB 599). We thank Markus Badenhop for excellent technical support and Christopher Müller for the design of .
PY - 2014/4
Y1 - 2014/4
N2 - In this in vitro study, magnesium plates of ZEK100 and MgCa0.8 alloy similar to common titanium alloy osteosynthesis plates were investigated as degradable biomedical materials with a focus on primary stability. Immersion tests were performed in Hank's Balanced Salt Solution at 37. The bending strength of the samples was determined using the four-point bending test according to ISO 9585:1990. The initial strength of the noncorroded ZEK100 plate was 11% greater than that of the MgCa0.8 plate; both were approximately 65% weaker than a titanium plate. The bending strength was determined after 48 and 96 h of immersion in Hank's Balanced Salt Solution; both magnesium alloys decreased by approximately 7% after immersion for 96 h. The degradation rate and the Mg2+ release of ZEK100 were lower than those of MgCa0.8. Strong pitting and filiform corrosion were observed in the MgCa0.8 samples after 96 h of immersion. The surface of the ZEK100 plates exhibited only small areas of filiform corrosion. The results of this in vitro study indicate that the ZEK100 alloy may be more suitable for biomedical applications.
AB - In this in vitro study, magnesium plates of ZEK100 and MgCa0.8 alloy similar to common titanium alloy osteosynthesis plates were investigated as degradable biomedical materials with a focus on primary stability. Immersion tests were performed in Hank's Balanced Salt Solution at 37. The bending strength of the samples was determined using the four-point bending test according to ISO 9585:1990. The initial strength of the noncorroded ZEK100 plate was 11% greater than that of the MgCa0.8 plate; both were approximately 65% weaker than a titanium plate. The bending strength was determined after 48 and 96 h of immersion in Hank's Balanced Salt Solution; both magnesium alloys decreased by approximately 7% after immersion for 96 h. The degradation rate and the Mg2+ release of ZEK100 were lower than those of MgCa0.8. Strong pitting and filiform corrosion were observed in the MgCa0.8 samples after 96 h of immersion. The surface of the ZEK100 plates exhibited only small areas of filiform corrosion. The results of this in vitro study indicate that the ZEK100 alloy may be more suitable for biomedical applications.
KW - corrosion
KW - implants
KW - In vitro
KW - magnesium
KW - orthopedic
UR - http://www.scopus.com/inward/record.url?scp=84898983785&partnerID=8YFLogxK
U2 - 10.1177/0885328213506758
DO - 10.1177/0885328213506758
M3 - Article
C2 - 24105427
AN - SCOPUS:84898983785
VL - 28
SP - 1264
EP - 1273
JO - Journal of Biomaterials Applications
JF - Journal of Biomaterials Applications
SN - 0885-3282
IS - 8
ER -