Details
| Original language | English |
|---|---|
| Title of host publication | 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society |
| Subtitle of host publication | Enabling Innovative Technologies for Global Healthcare, EMBC 2020 |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 2257-2261 |
| Number of pages | 5 |
| ISBN (electronic) | 9781728119908 |
| ISBN (print) | 9781728119908 |
| Publication status | Published - 2020 |
| Event | 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020 - Montreal, Canada Duration: 20 Jul 2020 → 24 Jul 2020 |
Publication series
| Name | Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS |
|---|---|
| Volume | 2020-July |
| ISSN (Print) | 1557-170X |
Abstract
In an aging society, diseases associated with irreversible damage of organs are frequent. An increasing percentage of patients requires bioartificial tissue or organ substitutes. Tissue engineering products depend on a well-defined process to ensure successful cultivation while meeting high regulatory demands. The goal of the presented work is the development of a bioreactor system for the cultivation of tissue-engineered vascular grafts (TEVGs) for autologous implantation and transition from a lab scale setup to standardized production. Key characteristics include (i) the automated reliable monitoring and control of a wide-range of parameters regarding implant conditioning, (ii) easy and sterile setup and operation, (iii) reasonable costs of disposables, and (iv) parallelization of automated cultivation processes. The presented prototype bioreactor system provides comprehensive physiologically conditioning, sensing, and imaging functionality to meet all requirements for the successful cultivation of vascular grafts on a productional scale.
ASJC Scopus subject areas
- Computer Science(all)
- Signal Processing
- Engineering(all)
- Biomedical Engineering
- Computer Science(all)
- Computer Vision and Pattern Recognition
- Medicine(all)
- Health Informatics
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42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society: Enabling Innovative Technologies for Global Healthcare, EMBC 2020. Institute of Electrical and Electronics Engineers Inc., 2020. p. 2257-2261 9175340 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2020-July).
Research output: Chapter in book/report/conference proceeding › Conference contribution › Research › peer review
}
TY - GEN
T1 - Automated Bioreactor System for the Cultivation of Autologous Tissue-Engineered Vascular Grafts
AU - Stanislawski, Nils
AU - Cholewa, Fabian
AU - Heymann, Henrik
AU - Kraus, Xenia
AU - Heene, Sebastian
AU - Witt, Martin
AU - Thoms, Stefanie
AU - Blume, Cornelia
AU - Blume, Holger
PY - 2020
Y1 - 2020
N2 - In an aging society, diseases associated with irreversible damage of organs are frequent. An increasing percentage of patients requires bioartificial tissue or organ substitutes. Tissue engineering products depend on a well-defined process to ensure successful cultivation while meeting high regulatory demands. The goal of the presented work is the development of a bioreactor system for the cultivation of tissue-engineered vascular grafts (TEVGs) for autologous implantation and transition from a lab scale setup to standardized production. Key characteristics include (i) the automated reliable monitoring and control of a wide-range of parameters regarding implant conditioning, (ii) easy and sterile setup and operation, (iii) reasonable costs of disposables, and (iv) parallelization of automated cultivation processes. The presented prototype bioreactor system provides comprehensive physiologically conditioning, sensing, and imaging functionality to meet all requirements for the successful cultivation of vascular grafts on a productional scale.
AB - In an aging society, diseases associated with irreversible damage of organs are frequent. An increasing percentage of patients requires bioartificial tissue or organ substitutes. Tissue engineering products depend on a well-defined process to ensure successful cultivation while meeting high regulatory demands. The goal of the presented work is the development of a bioreactor system for the cultivation of tissue-engineered vascular grafts (TEVGs) for autologous implantation and transition from a lab scale setup to standardized production. Key characteristics include (i) the automated reliable monitoring and control of a wide-range of parameters regarding implant conditioning, (ii) easy and sterile setup and operation, (iii) reasonable costs of disposables, and (iv) parallelization of automated cultivation processes. The presented prototype bioreactor system provides comprehensive physiologically conditioning, sensing, and imaging functionality to meet all requirements for the successful cultivation of vascular grafts on a productional scale.
UR - http://www.scopus.com/inward/record.url?scp=85091033798&partnerID=8YFLogxK
U2 - 10.1109/embc44109.2020.9175340
DO - 10.1109/embc44109.2020.9175340
M3 - Conference contribution
SN - 9781728119908
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 2257
EP - 2261
BT - 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020
Y2 - 20 July 2020 through 24 July 2020
ER -