In situ characterization of polycaprolactone fiber response to quasi-static tensile loading in scanning electron microscopy

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • Alexander Delp
  • Alexander Becker
  • Daniel Hülsbusch
  • Ronja Scholz
  • Marc Müller
  • Birgit Glasmacher
  • Frank Walther

Organisationseinheiten

Externe Organisationen

  • Technische Universität Dortmund
  • NIFE- Niedersächsisches Zentrum für Biomedizintechnik, Implantatforschung und Entwicklung
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Details

OriginalspracheEnglisch
Aufsatznummer2090
FachzeitschriftPolymers
Jahrgang13
Ausgabenummer13
PublikationsstatusVeröffentlicht - 24 Juni 2021

Abstract

Microstructural responses to the mechanical load of polymers used in tissue engineering is notably important for qualification at in vivo testing, although insufficiently studied, especially regarding promising polycaprolactone (PCL). For further investigations, electrospun PCL scaffolds with different degrees of fiber alignment were produced, using two discrete relative drum collector velocities. Development and preparation of an adjusted sample geometry enabled in situ tensile testing in scanning electron microscopy. By analyzing the microstructure and the use of selected tracking techniques, it was possible to visualize and quantify fiber/fiber area displacements as well as local fractures of single PCL fibers, considering quasi-static tensile load and fiber alignment. The possibility of displacement determination using in situ scanning electron microscopy techniques for testing fibrous PCL scaffolds was introduced and quantified.

ASJC Scopus Sachgebiete

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In situ characterization of polycaprolactone fiber response to quasi-static tensile loading in scanning electron microscopy. / Delp, Alexander; Becker, Alexander; Hülsbusch, Daniel et al.
in: Polymers, Jahrgang 13, Nr. 13, 2090, 24.06.2021.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Delp, A, Becker, A, Hülsbusch, D, Scholz, R, Müller, M, Glasmacher, B & Walther, F 2021, 'In situ characterization of polycaprolactone fiber response to quasi-static tensile loading in scanning electron microscopy', Polymers, Jg. 13, Nr. 13, 2090. https://doi.org/10.3390/polym13132090
Delp, A., Becker, A., Hülsbusch, D., Scholz, R., Müller, M., Glasmacher, B., & Walther, F. (2021). In situ characterization of polycaprolactone fiber response to quasi-static tensile loading in scanning electron microscopy. Polymers, 13(13), Artikel 2090. https://doi.org/10.3390/polym13132090
Delp A, Becker A, Hülsbusch D, Scholz R, Müller M, Glasmacher B et al. In situ characterization of polycaprolactone fiber response to quasi-static tensile loading in scanning electron microscopy. Polymers. 2021 Jun 24;13(13):2090. doi: 10.3390/polym13132090
Delp, Alexander ; Becker, Alexander ; Hülsbusch, Daniel et al. / In situ characterization of polycaprolactone fiber response to quasi-static tensile loading in scanning electron microscopy. in: Polymers. 2021 ; Jahrgang 13, Nr. 13.
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title = "In situ characterization of polycaprolactone fiber response to quasi-static tensile loading in scanning electron microscopy",
abstract = "Microstructural responses to the mechanical load of polymers used in tissue engineering is notably important for qualification at in vivo testing, although insufficiently studied, especially regarding promising polycaprolactone (PCL). For further investigations, electrospun PCL scaffolds with different degrees of fiber alignment were produced, using two discrete relative drum collector velocities. Development and preparation of an adjusted sample geometry enabled in situ tensile testing in scanning electron microscopy. By analyzing the microstructure and the use of selected tracking techniques, it was possible to visualize and quantify fiber/fiber area displacements as well as local fractures of single PCL fibers, considering quasi-static tensile load and fiber alignment. The possibility of displacement determination using in situ scanning electron microscopy techniques for testing fibrous PCL scaffolds was introduced and quantified.",
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AU - Scholz, Ronja

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AU - Glasmacher, Birgit

AU - Walther, Frank

N1 - Funding Information: The research project is supported by the DFG in the framework of the Research Unit 2180 “Graded Implants for Tendon-Bone Junctions”. Acknowledgments: We acknowledge financial support by Deutsche Forschungsgemeinschaft and Technische Universität Dortmund/TU Dortmund University within the funding programme Open Access Publishing. We thank Michael Bode, Miriam Walter and Gioia Busse for their great support.

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KW - In situ tensile testing

KW - Microstructure

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