Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 163-177 |
| Seitenumfang | 15 |
| Fachzeitschrift | Arkivoc |
| Jahrgang | 2019 |
| Ausgabenummer | 5 |
| Frühes Online-Datum | 17 März 2019 |
| Publikationsstatus | Veröffentlicht - 2019 |
Abstract
A concise and efficient approach to tetrakis(uracil) derivatives by the reaction of bis(aldehydes) with four equivalents of 6-aminouracil is reported. Also, the synthesis of bis(pyrimido[4,5-b]quinolones) and bis(indeno-[2',1':5,6]pyrido[2,3-d]pyrimidine) derivatives has been accomplished by a three-component reaction involving bis(aldehydes), 6-aminouracil and the appropriate cyclic 1,3-diketone. The method involves domino Knoevenagel condensation / Michael addition reaction sequences.
ASJC Scopus Sachgebiete
- Chemie (insg.)
- Organische Chemie
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in: Arkivoc, Jahrgang 2019, Nr. 5, 2019, S. 163-177.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - An efficient one-pot three-component synthesis of tetrakis(uracil) and their corresponding bis-fused derivatives
AU - Abdelmoniem, Amr M.
AU - Ghozlan, Said A.S.
AU - Butenschön, Holger
AU - Abdelmoniem, Doaa M.
AU - Elwahy, Ahmed H.M.
AU - Abdelhamid, Ismail A.
PY - 2019
Y1 - 2019
N2 - A concise and efficient approach to tetrakis(uracil) derivatives by the reaction of bis(aldehydes) with four equivalents of 6-aminouracil is reported. Also, the synthesis of bis(pyrimido[4,5-b]quinolones) and bis(indeno-[2',1':5,6]pyrido[2,3-d]pyrimidine) derivatives has been accomplished by a three-component reaction involving bis(aldehydes), 6-aminouracil and the appropriate cyclic 1,3-diketone. The method involves domino Knoevenagel condensation / Michael addition reaction sequences.
AB - A concise and efficient approach to tetrakis(uracil) derivatives by the reaction of bis(aldehydes) with four equivalents of 6-aminouracil is reported. Also, the synthesis of bis(pyrimido[4,5-b]quinolones) and bis(indeno-[2',1':5,6]pyrido[2,3-d]pyrimidine) derivatives has been accomplished by a three-component reaction involving bis(aldehydes), 6-aminouracil and the appropriate cyclic 1,3-diketone. The method involves domino Knoevenagel condensation / Michael addition reaction sequences.
KW - Bis(aldehydes)
KW - Fused pyrimidines
KW - Indenones
KW - Michael addition
KW - Quinolinones
KW - Uracils
UR - http://www.scopus.com/inward/record.url?scp=85065449059&partnerID=8YFLogxK
U2 - 10.24820/ark.5550190.p010.875
DO - 10.24820/ark.5550190.p010.875
M3 - Article
AN - SCOPUS:85065449059
VL - 2019
SP - 163
EP - 177
JO - Arkivoc
JF - Arkivoc
SN - 1551-7004
IS - 5
ER -