Details
| Original language | English |
|---|---|
| Title of host publication | Advances in Biochemical Engineering/Biotechnology |
| Editors | Dr. Janina Bahnemann, Dr. Alexander Grünberger |
| Pages | 1-16 |
| Number of pages | 16 |
| ISBN (electronic) | 978-3-031-04188-4 |
| Publication status | Published - 2022 |
Publication series
| Name | Advances in Biochemical Engineering/Biotechnology |
|---|---|
| Volume | 179 |
| ISSN (Print) | 0724-6145 |
| ISSN (electronic) | 1616-8542 |
Abstract
Microfluidics has emerged as a powerful tool, enabling biotechnological processes to be performed on a microscale where certain physical processes (such as laminar flow, surface-to-volume ratio, and surface interactions) become dominant factors. At the same time, volumes and assay times are also reduced in microscale – which can substantially lower experimental costs. A decade ago, most microfluidic systems were only used for proof-of-concept studies; today, a wide array of microfluidic systems have been deployed to tackle various biotechnological research questions – especially regarding the analysis, screening, and understanding of cellular systems. Examples cover all biotechnological areas, from diagnostic applications in the field of medical biotechnology to the screening of potentially useful cells in the field of industrial biotechnology. As part of this review, we provide a brief introduction to microfluidics technology (including the vision of Lab-on-a-chip (LOC) systems) and survey some of the most notable applications of microfluidic technology in biotechnology to date.
Keywords
- Biomicrofluidics, Biotechnology, Lab-on-a-chip, Microfluidics, Microsystems integration, Point-of-care diagnostic, Single-cell analysis
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
- Chemical Engineering(all)
- Bioengineering
- Immunology and Microbiology(all)
- Applied Microbiology and Biotechnology
Cite this
- Standard
- Harvard
- Apa
- Vancouver
- BibTeX
- RIS
Advances in Biochemical Engineering/Biotechnology. ed. / Dr. Janina Bahnemann; Dr. Alexander Grünberger. 2022. p. 1-16 (Advances in Biochemical Engineering/Biotechnology; Vol. 179).
Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
}
TY - CHAP
T1 - Microfluidics in Biotechnology
T2 - Overview and Status Quo
AU - Bahnemann, Janina
AU - Grünberger, Alexander
N1 - Acknowledgment: The authors would like to thank Steffen Winkler for the design and creation of Fig. 3, and Julian Schmitz for the design and creation of the icons for the different biotechnology fields (see Fig. 4). We furthermore would like to thank Christopher Heuer for proof-reading this manuscript.
PY - 2022
Y1 - 2022
N2 - Microfluidics has emerged as a powerful tool, enabling biotechnological processes to be performed on a microscale where certain physical processes (such as laminar flow, surface-to-volume ratio, and surface interactions) become dominant factors. At the same time, volumes and assay times are also reduced in microscale – which can substantially lower experimental costs. A decade ago, most microfluidic systems were only used for proof-of-concept studies; today, a wide array of microfluidic systems have been deployed to tackle various biotechnological research questions – especially regarding the analysis, screening, and understanding of cellular systems. Examples cover all biotechnological areas, from diagnostic applications in the field of medical biotechnology to the screening of potentially useful cells in the field of industrial biotechnology. As part of this review, we provide a brief introduction to microfluidics technology (including the vision of Lab-on-a-chip (LOC) systems) and survey some of the most notable applications of microfluidic technology in biotechnology to date.
AB - Microfluidics has emerged as a powerful tool, enabling biotechnological processes to be performed on a microscale where certain physical processes (such as laminar flow, surface-to-volume ratio, and surface interactions) become dominant factors. At the same time, volumes and assay times are also reduced in microscale – which can substantially lower experimental costs. A decade ago, most microfluidic systems were only used for proof-of-concept studies; today, a wide array of microfluidic systems have been deployed to tackle various biotechnological research questions – especially regarding the analysis, screening, and understanding of cellular systems. Examples cover all biotechnological areas, from diagnostic applications in the field of medical biotechnology to the screening of potentially useful cells in the field of industrial biotechnology. As part of this review, we provide a brief introduction to microfluidics technology (including the vision of Lab-on-a-chip (LOC) systems) and survey some of the most notable applications of microfluidic technology in biotechnology to date.
KW - Biomicrofluidics
KW - Biotechnology
KW - Lab-on-a-chip
KW - Microfluidics
KW - Microsystems integration
KW - Point-of-care diagnostic
KW - Single-cell analysis
UR - http://www.scopus.com/inward/record.url?scp=85135378028&partnerID=8YFLogxK
U2 - 10.1007/10_2022_206
DO - 10.1007/10_2022_206
M3 - Contribution to book/anthology
C2 - 35333948
AN - SCOPUS:85135378028
SN - 978-3-031-04187-7
T3 - Advances in Biochemical Engineering/Biotechnology
SP - 1
EP - 16
BT - Advances in Biochemical Engineering/Biotechnology
A2 - Bahnemann, Dr. Janina
A2 - Grünberger, Dr. Alexander
ER -