Details
Original language | English |
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Title of host publication | Engineering Natural Product Biosynthesis |
Subtitle of host publication | Methods and Protocols |
Editors | Elizabeth Skellam |
Pages | 435-448 |
Number of pages | 14 |
ISBN (electronic) | 978-1-0716-2273-5 |
Publication status | Published - 7 May 2022 |
Publication series
Name | Methods in Molecular Biology |
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Volume | 2489 |
ISSN (Print) | 1064-3745 |
ISSN (electronic) | 1940-6029 |
Abstract
Protein microarrays are useful tools for detecting the presence of a target where different prey and bait combinations exist. Here we describe the extended application for a functional target-oriented screening assay with full length Heat shock proteins (HSPs) for the identification of novel compounds.
Keywords
- Anti HSP90 inhibitor, ATP-Cy5, Heat shock proteins, Natural products, Protein microarray
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Molecular Biology
- Biochemistry, Genetics and Molecular Biology(all)
- Genetics
Cite this
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Engineering Natural Product Biosynthesis : Methods and Protocols. ed. / Elizabeth Skellam. 2022. p. 435-448 (Methods in Molecular Biology; Vol. 2489).
Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
}
TY - CHAP
T1 - Microarray-Based Screening of Putative HSP90 Inhibitors Predicted and Isolated from Microorganisms
AU - Kishore, Anusha
AU - Fetter, Artem
AU - Zeilinger, Carsten
PY - 2022/5/7
Y1 - 2022/5/7
N2 - Protein microarrays are useful tools for detecting the presence of a target where different prey and bait combinations exist. Here we describe the extended application for a functional target-oriented screening assay with full length Heat shock proteins (HSPs) for the identification of novel compounds.
AB - Protein microarrays are useful tools for detecting the presence of a target where different prey and bait combinations exist. Here we describe the extended application for a functional target-oriented screening assay with full length Heat shock proteins (HSPs) for the identification of novel compounds.
KW - Anti HSP90 inhibitor
KW - ATP-Cy5
KW - Heat shock proteins
KW - Natural products
KW - Protein microarray
UR - http://www.scopus.com/inward/record.url?scp=85130003351&partnerID=8YFLogxK
U2 - 10.1007/978-1-0716-2273-5_22
DO - 10.1007/978-1-0716-2273-5_22
M3 - Contribution to book/anthology
C2 - 35524063
AN - SCOPUS:85130003351
SN - 978-1-0716-2272-8
T3 - Methods in Molecular Biology
SP - 435
EP - 448
BT - Engineering Natural Product Biosynthesis
A2 - Skellam, Elizabeth
ER -