Details
| Original language | English |
|---|---|
| Article number | e2300013 |
| Number of pages | 13 |
| Journal | Engineering in life sciences |
| Volume | 23 |
| Issue number | 11 |
| Publication status | Published - 8 Nov 2023 |
Abstract
The increased occurrence of antibiotic resistance and the harmful use of pesticides are a major problem of modern times. A ban on the use of antibiotics as growth promoters in animal breeding has put a focus on the probiotics market. Probiotic food supplements are versatile and show promising results in animal and human nutrition. Chemical pesticides can be substituted by biopesticides, which are very effective against various pests in plants due to increased research. What these fields have in common is the use of spore-forming bacteria. The endospore-forming Bacillus spp. belonging to this group offer an effective solution to the aforementioned problems. Therefore, the biotechnological production of sufficient qualities of such endospores has become an innovative and financially viable field of research. In this review, the production of different Bacillus spp. endospores will be reviewed. For this purpose, the media compositions, cultivation conditions and bioprocess optimization methods of the last 20 years are presented and reflected.
Keywords
- Bacillus, bioprocess development, industrial, optimization, spore production
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
- Chemical Engineering(all)
- Bioengineering
- Environmental Science(all)
- Environmental Engineering
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In: Engineering in life sciences, Vol. 23, No. 11, e2300013, 08.11.2023.
Research output: Contribution to journal › Review article › Research › peer review
}
TY - JOUR
T1 - Endospore production of Bacillus spp. for industrial use
AU - Biermann, Riekje
AU - Beutel, Sascha
N1 - Funding Information: The authors would like to thank the Open Access fund of Leibniz University Hannover for the funding of the publication of this article. The authors would also like to thank Tessa Habich for her support with the depictions in this review. Open access funding enabled and organized by Projekt DEAL.
PY - 2023/11/8
Y1 - 2023/11/8
N2 - The increased occurrence of antibiotic resistance and the harmful use of pesticides are a major problem of modern times. A ban on the use of antibiotics as growth promoters in animal breeding has put a focus on the probiotics market. Probiotic food supplements are versatile and show promising results in animal and human nutrition. Chemical pesticides can be substituted by biopesticides, which are very effective against various pests in plants due to increased research. What these fields have in common is the use of spore-forming bacteria. The endospore-forming Bacillus spp. belonging to this group offer an effective solution to the aforementioned problems. Therefore, the biotechnological production of sufficient qualities of such endospores has become an innovative and financially viable field of research. In this review, the production of different Bacillus spp. endospores will be reviewed. For this purpose, the media compositions, cultivation conditions and bioprocess optimization methods of the last 20 years are presented and reflected.
AB - The increased occurrence of antibiotic resistance and the harmful use of pesticides are a major problem of modern times. A ban on the use of antibiotics as growth promoters in animal breeding has put a focus on the probiotics market. Probiotic food supplements are versatile and show promising results in animal and human nutrition. Chemical pesticides can be substituted by biopesticides, which are very effective against various pests in plants due to increased research. What these fields have in common is the use of spore-forming bacteria. The endospore-forming Bacillus spp. belonging to this group offer an effective solution to the aforementioned problems. Therefore, the biotechnological production of sufficient qualities of such endospores has become an innovative and financially viable field of research. In this review, the production of different Bacillus spp. endospores will be reviewed. For this purpose, the media compositions, cultivation conditions and bioprocess optimization methods of the last 20 years are presented and reflected.
KW - Bacillus
KW - bioprocess development
KW - industrial
KW - optimization
KW - spore production
UR - http://www.scopus.com/inward/record.url?scp=85174151069&partnerID=8YFLogxK
U2 - 10.1002/elsc.202300013
DO - 10.1002/elsc.202300013
M3 - Review article
AN - SCOPUS:85174151069
VL - 23
JO - Engineering in life sciences
JF - Engineering in life sciences
SN - 1618-0240
IS - 11
M1 - e2300013
ER -