Details
| Original language | English |
|---|---|
| Title of host publication | Encyclopedia of Biomedical Engineering |
| Editors | Roger Narayan |
| Publisher | Elsevier |
| Pages | 81-110 |
| Number of pages | 30 |
| Volume | 1-3 |
| ISBN (Electronic) | 9780128051443 |
| ISBN (Print) | 9780128048290 |
| Publication status | Published - 2019 |
Abstract
The mechanical response of soft tissues is characterized by nonlinear stress-strain relationships associated with the peculiar mechanical properties of constituents which are structured in a hierarchical multiscale arrangement. Relevant anisotropic properties are inherited from structural heterogeneities associated with significant differences in the stiffness of constituents. Moreover, the high water content endows soft tissues by incompressible or quasi-incompressible behavior. Finally, tissue mechanics can be also affected by inelastic mechanisms, such as damage and viscous effects, as well as active responses, growth, and remodeling. The effective description of tissue mechanics, i.e. the constitutive model, is instrumental in the development of reliable computational models for biomechanical analyses. Present work addresses the fundamental theoretical aspects for the development of constitutive models of soft tissues. Both elastic and inelastic responses are faced. Modeling strategies are discussed in terms of physical requirements, thermodynamical consistency, and mathematical prescriptions. A snapshot of the state of the art is presented, with a focus on multiscale approaches. The latter allow indeed to gain a special insight on the structure-mechanics relationship that characterizes soft tissue response in pathophysiological conditions.
Keywords
- Active response, Anisotropic behavior, Constitutive models, Continuum mechanics, Damage, Growth and remodeling, Hyperelasticity, Incompressibility, Invariant-based formulation, Multiscale approaches, Plasticity, Soft tissues, Structure-mechanics relationship, Thermodynamic requirements, Viscoelasticity
ASJC Scopus subject areas
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Encyclopedia of Biomedical Engineering. ed. / Roger Narayan. Vol. 1-3 Elsevier, 2019. p. 81-110.
Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
}
TY - CHAP
T1 - Constitutive modeling of soft tissues
AU - Marino, Michele
PY - 2019
Y1 - 2019
N2 - The mechanical response of soft tissues is characterized by nonlinear stress-strain relationships associated with the peculiar mechanical properties of constituents which are structured in a hierarchical multiscale arrangement. Relevant anisotropic properties are inherited from structural heterogeneities associated with significant differences in the stiffness of constituents. Moreover, the high water content endows soft tissues by incompressible or quasi-incompressible behavior. Finally, tissue mechanics can be also affected by inelastic mechanisms, such as damage and viscous effects, as well as active responses, growth, and remodeling. The effective description of tissue mechanics, i.e. the constitutive model, is instrumental in the development of reliable computational models for biomechanical analyses. Present work addresses the fundamental theoretical aspects for the development of constitutive models of soft tissues. Both elastic and inelastic responses are faced. Modeling strategies are discussed in terms of physical requirements, thermodynamical consistency, and mathematical prescriptions. A snapshot of the state of the art is presented, with a focus on multiscale approaches. The latter allow indeed to gain a special insight on the structure-mechanics relationship that characterizes soft tissue response in pathophysiological conditions.
AB - The mechanical response of soft tissues is characterized by nonlinear stress-strain relationships associated with the peculiar mechanical properties of constituents which are structured in a hierarchical multiscale arrangement. Relevant anisotropic properties are inherited from structural heterogeneities associated with significant differences in the stiffness of constituents. Moreover, the high water content endows soft tissues by incompressible or quasi-incompressible behavior. Finally, tissue mechanics can be also affected by inelastic mechanisms, such as damage and viscous effects, as well as active responses, growth, and remodeling. The effective description of tissue mechanics, i.e. the constitutive model, is instrumental in the development of reliable computational models for biomechanical analyses. Present work addresses the fundamental theoretical aspects for the development of constitutive models of soft tissues. Both elastic and inelastic responses are faced. Modeling strategies are discussed in terms of physical requirements, thermodynamical consistency, and mathematical prescriptions. A snapshot of the state of the art is presented, with a focus on multiscale approaches. The latter allow indeed to gain a special insight on the structure-mechanics relationship that characterizes soft tissue response in pathophysiological conditions.
KW - Active response
KW - Anisotropic behavior
KW - Constitutive models
KW - Continuum mechanics
KW - Damage
KW - Growth and remodeling
KW - Hyperelasticity
KW - Incompressibility
KW - Invariant-based formulation
KW - Multiscale approaches
KW - Plasticity
KW - Soft tissues
KW - Structure-mechanics relationship
KW - Thermodynamic requirements
KW - Viscoelasticity
UR - http://www.scopus.com/inward/record.url?scp=85066016603&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-801238-3.99926-4
DO - 10.1016/B978-0-12-801238-3.99926-4
M3 - Contribution to book/anthology
AN - SCOPUS:85066016603
SN - 9780128048290
VL - 1-3
SP - 81
EP - 110
BT - Encyclopedia of Biomedical Engineering
A2 - Narayan, Roger
PB - Elsevier
ER -