Details
| Original language | English |
|---|---|
| Title of host publication | Advances in Experimental Medicine and Biology |
| Pages | 1-40 |
| Number of pages | 40 |
| Publication status | Published - 2019 |
| Externally published | Yes |
Publication series
| Name | Advances in Experimental Medicine and Biology |
|---|---|
| Volume | 1101 |
| ISSN (Print) | 0065-2598 |
| ISSN (electronic) | 2214-8019 |
Abstract
The Utah electrode array (UEA) and its many derivatives have become a gold standard for high-channel count bi-directional neural interfaces, in particular in human subject applications. The chapter provides a brief overview of leading electrode concepts and the context in which the UEA has to be understood. It goes on to discuss the key advances and developments of the UEA platform in the past 15 years, as well as novel wireless and system integration technologies that will merge into future generations of fully integrated devices. Aspects covered include novel device architectures that allow scaling of channel count and density of electrode contacts, material improvements to substrate, electrode contacts, and encapsulation. Further subjects are adaptations of the UEA platform to support IR and optogenetic simulation as well as an improved understanding of failure modes and methods to test and accelerate degradation in vitro such as to better predict device failure and lifetime in vivo.
Keywords
- Accelerated aging, Advanced system integration, Neural interface materials, Utah electrode array (UEA), Wireless technology
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- General Biochemistry,Genetics and Molecular Biology
Cite this
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Advances in Experimental Medicine and Biology. 2019. p. 1-40 (Advances in Experimental Medicine and Biology; Vol. 1101).
Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
}
TY - CHAP
T1 - Advances in penetrating multichannel microelectrodes based on the Utah array platform
AU - Leber, Moritz
AU - Körner, Julia
AU - Reiche, Christopher F.
AU - Yin, Ming
AU - Bhandari, Rajmohan
AU - Franklin, Robert
AU - Negi, Sandeep
AU - Solzbacher, Florian
N1 - Publisher Copyright: © Springer Nature Singapore Pte Ltd 2019.
PY - 2019
Y1 - 2019
N2 - The Utah electrode array (UEA) and its many derivatives have become a gold standard for high-channel count bi-directional neural interfaces, in particular in human subject applications. The chapter provides a brief overview of leading electrode concepts and the context in which the UEA has to be understood. It goes on to discuss the key advances and developments of the UEA platform in the past 15 years, as well as novel wireless and system integration technologies that will merge into future generations of fully integrated devices. Aspects covered include novel device architectures that allow scaling of channel count and density of electrode contacts, material improvements to substrate, electrode contacts, and encapsulation. Further subjects are adaptations of the UEA platform to support IR and optogenetic simulation as well as an improved understanding of failure modes and methods to test and accelerate degradation in vitro such as to better predict device failure and lifetime in vivo.
AB - The Utah electrode array (UEA) and its many derivatives have become a gold standard for high-channel count bi-directional neural interfaces, in particular in human subject applications. The chapter provides a brief overview of leading electrode concepts and the context in which the UEA has to be understood. It goes on to discuss the key advances and developments of the UEA platform in the past 15 years, as well as novel wireless and system integration technologies that will merge into future generations of fully integrated devices. Aspects covered include novel device architectures that allow scaling of channel count and density of electrode contacts, material improvements to substrate, electrode contacts, and encapsulation. Further subjects are adaptations of the UEA platform to support IR and optogenetic simulation as well as an improved understanding of failure modes and methods to test and accelerate degradation in vitro such as to better predict device failure and lifetime in vivo.
KW - Accelerated aging
KW - Advanced system integration
KW - Neural interface materials
KW - Utah electrode array (UEA)
KW - Wireless technology
UR - http://www.scopus.com/inward/record.url?scp=85075114752&partnerID=8YFLogxK
U2 - 10.1007/978-981-13-2050-7_1
DO - 10.1007/978-981-13-2050-7_1
M3 - Contribution to book/anthology
C2 - 31729670
AN - SCOPUS:85075114752
T3 - Advances in Experimental Medicine and Biology
SP - 1
EP - 40
BT - Advances in Experimental Medicine and Biology
ER -