A note on Welch's approximate t-solution to bioequivalence assessment

Research output: Contribution to journal › Article › Research › peer review

Authors

  • Dieter Hauschke
  • Volker W. Steinijans
  • Ludwig A. Hothorn

Research Organisations

External Research Organisations

  • Altana Pharma
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Details

Original languageEnglish
Pages (from-to)236-237
Number of pages2
JournalBIOMETRIKA
Volume83
Issue number1
Publication statusPublished - 1 Mar 1996

Abstract

The crossover is considered to be the design of choice for bioequivalence studies and regulatory authorities currently require evidence of average bioequivalence which is a special case of population bioequivalence. To assess average bioequivalence, the double t-test can be performed without Welch's approximation.

Keywords

    Bioequivalence, Double t-test, Heterogeneous variances, Welch's approximate t-solution

ASJC Scopus subject areas

Cite this

A note on Welch's approximate t-solution to bioequivalence assessment. / Hauschke, Dieter; Steinijans, Volker W.; Hothorn, Ludwig A.
In: BIOMETRIKA, Vol. 83, No. 1, 01.03.1996, p. 236-237.

Research output: Contribution to journal › Article › Research › peer review

Hauschke, D, Steinijans, VW & Hothorn, LA 1996, 'A note on Welch's approximate t-solution to bioequivalence assessment', BIOMETRIKA, vol. 83, no. 1, pp. 236-237. https://doi.org/10.1093/biomet/83.1.236
Hauschke, D., Steinijans, V. W., & Hothorn, L. A. (1996). A note on Welch's approximate t-solution to bioequivalence assessment. BIOMETRIKA, 83(1), 236-237. https://doi.org/10.1093/biomet/83.1.236
Hauschke D, Steinijans VW, Hothorn LA. A note on Welch's approximate t-solution to bioequivalence assessment. BIOMETRIKA. 1996 Mar 1;83(1):236-237. doi: 10.1093/biomet/83.1.236
Hauschke, Dieter ; Steinijans, Volker W. ; Hothorn, Ludwig A. / A note on Welch's approximate t-solution to bioequivalence assessment. In: BIOMETRIKA. 1996 ; Vol. 83, No. 1. pp. 236-237.
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