Sequential and Multiple Testing for Dose-Response Analysis

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • Walter Lehmacher
  • Meinhard Kieser
  • Ludwig Hothorn

Organisationseinheiten

Externe Organisationen

  • Universität zu Köln
  • Ingenieurbüro Lohmeyer GmbH and Co. KG
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Details

OriginalspracheEnglisch
Seiten (von - bis)591-597
Seitenumfang7
FachzeitschriftTherapeutic Innovation & Regulatory Science
Jahrgang34
Ausgabenummer2
PublikationsstatusVeröffentlicht - 30 Dez. 2000

Abstract

For the analysis of dose-response relationship under the assumption of ordered alternatives several global trend tests are available. Furthermore, there are multiple test procedures which can identify doses as effective or even as minimally effective. In this paper it is shown that the principles of multiple comparisons and interim analyses can be combined inflexible and adaptive strategies for dose-response analyses; these procedures control the experimentwise error rate.

ASJC Scopus Sachgebiete

Ziele für nachhaltige Entwicklung

Zitieren

Sequential and Multiple Testing for Dose-Response Analysis. / Lehmacher, Walter; Kieser, Meinhard; Hothorn, Ludwig.
in: Therapeutic Innovation & Regulatory Science, Jahrgang 34, Nr. 2, 30.12.2000, S. 591-597.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Lehmacher W, Kieser M, Hothorn L. Sequential and Multiple Testing for Dose-Response Analysis. Therapeutic Innovation & Regulatory Science. 2000 Dez 30;34(2):591-597. doi: 10.1177/009286150003400227, 10.15488/3045
Lehmacher, Walter ; Kieser, Meinhard ; Hothorn, Ludwig. / Sequential and Multiple Testing for Dose-Response Analysis. in: Therapeutic Innovation & Regulatory Science. 2000 ; Jahrgang 34, Nr. 2. S. 591-597.
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