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Extending the Measurement Range in Ophthalmic Linear Optical Coherence Tomography using Dual Reference Path Interferometry

Publikation: Beitrag in Buch/Bericht/Sammelwerk/KonferenzbandAufsatz in KonferenzbandForschungPeer-Review

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OriginalspracheEnglisch
Titel des SammelwerksOphthalmic Technologies XXXV
Herausgeber/-innenDaniel X. Hammer, Derek Nankivil, Yuankai K. Tao
Herausgeber (Verlag)SPIE
ISBN (elektronisch)9781510683488
PublikationsstatusVeröffentlicht - 19 März 2025
VeranstaltungSPIE Photonics West BiOS 2025 - San Francisco, USA / Vereinigte Staaten
Dauer: 25 Jan. 202531 Jan. 2025

Publikationsreihe

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Band13300
ISSN (Print)1605-7422

Abstract

A fiber-based linear optical coherence tomography (LOCT) system employing a cost-effective CMOS camera has previously demonstrated high-resolution imaging suitable for retinal screening, including glaucoma monitoring. However, the system’s imaging depth was constrained to approximately 400 µm, insufficient for depth imaging of the optic nerve head (ONH), due to limitations imposed by the camera’s sensor size and pixel pitch. To overcome this limitation without replacing the economical and available sensor, we present a modification to the reference arm. By optimizing the utilization of the camera sensor’s vertical dimension, the system achieves an extended imaging depth, enabling the visualization of deeper tissue structures. Validation using an artificial eye model confirms that the modified LOCT system significantly enhances imaging depth while maintaining B-Scan quality. This advancement offers a cost-effective approach to extend the measurement range of LOCT systems, broadening their applicability in retinal imaging without altering the actual imaging sensor.

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Extending the Measurement Range in Ophthalmic Linear Optical Coherence Tomography using Dual Reference Path Interferometry. / Bauer, Niklas; Harings, David; Mendroch, Damian et al.
Ophthalmic Technologies XXXV. Hrsg. / Daniel X. Hammer; Derek Nankivil; Yuankai K. Tao. SPIE, 2025. 133000I (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Band 13300).

Publikation: Beitrag in Buch/Bericht/Sammelwerk/KonferenzbandAufsatz in KonferenzbandForschungPeer-Review

Bauer, N, Harings, D, Mendroch, D, Matrisch, J, Oberheide, U & Heisterkamp, A 2025, Extending the Measurement Range in Ophthalmic Linear Optical Coherence Tomography using Dual Reference Path Interferometry. in DX Hammer, D Nankivil & YK Tao (Hrsg.), Ophthalmic Technologies XXXV., 133000I, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Bd. 13300, SPIE, SPIE Photonics West BiOS 2025, San Francisco, California, USA / Vereinigte Staaten, 25 Jan. 2025. https://doi.org/10.1117/12.3046633
Bauer, N., Harings, D., Mendroch, D., Matrisch, J., Oberheide, U., & Heisterkamp, A. (2025). Extending the Measurement Range in Ophthalmic Linear Optical Coherence Tomography using Dual Reference Path Interferometry. In D. X. Hammer, D. Nankivil, & Y. K. Tao (Hrsg.), Ophthalmic Technologies XXXV Artikel 133000I (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Band 13300). SPIE. https://doi.org/10.1117/12.3046633
Bauer N, Harings D, Mendroch D, Matrisch J, Oberheide U, Heisterkamp A. Extending the Measurement Range in Ophthalmic Linear Optical Coherence Tomography using Dual Reference Path Interferometry. in Hammer DX, Nankivil D, Tao YK, Hrsg., Ophthalmic Technologies XXXV. SPIE. 2025. 133000I. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.3046633
Bauer, Niklas ; Harings, David ; Mendroch, Damian et al. / Extending the Measurement Range in Ophthalmic Linear Optical Coherence Tomography using Dual Reference Path Interferometry. Ophthalmic Technologies XXXV. Hrsg. / Daniel X. Hammer ; Derek Nankivil ; Yuankai K. Tao. SPIE, 2025. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
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