Publications
2024
- Published
Enhancing chemotherapeutic efficacy: Niosome-encapsulated Dox-Cis with MUC-1 aptamer
Barlas, F. B., Olceroglu, B., Ag Seleci, D., Gumus, Z. P., Siyah, P., Dabbek, M., Garnweitne, G., Stahl, F., Scheper, T. & Timur, S., 9 Aug 2024, In: Cancer medicine. 13, 15, 10 p., e70079.Research output: Contribution to journal › Article › Research › peer review
- Published
A Novel Artificial Coronary Plaque to Model Coronary Heart Disease
Lindenhahn, P., Richter, J., Pepelanova, I., Seeger, B., Volk, H. A., Hinkel, R., Hiebl, B., Scheper, T., Hinrichs, J. B., Becker, L. S., Haverich, A. & Kaufeld, T., 26 Mar 2024, In: Biomimetics. 9, 4, 15 p., 197.Research output: Contribution to journal › Article › Research › peer review
2023
- Published
Photonic Si microwell architectures for rapid antifungal susceptibility determination of Candida auris
Heuer, C., Jiang, X., Ron, G., Ternyak, O., Scheper, T., Bahnemann, J. & Segal, E., 27 Dec 2023, In: Chemical communications. 60, 10, p. 1305-1308 4 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Establishment of a Perfusion Process with Antibody-Producing CHO Cells Using a 3D-Printed Microfluidic Spiral Separator with Web-Based Flow Control
Schellenberg, J., Dehne, M., Lange, F., Scheper, T., Solle, D. & Bahnemann, J., Jun 2023, In: Bioengineering. 10, 6, 656.Research output: Contribution to journal › Article › Research › peer review
- Published
Digitale Zwillinge in der Bioprozesstechnik – Chancen und Möglichkeiten
RIchter, J., Lange, F., Scheper, T., Solle, D. & Beutel, S., 22 Mar 2023, In: Chemie-Ingenieur-Technik. 95, 4, p. 498-510 13 p.Research output: Contribution to journal › Article › Research
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Employing QbD strategies to assess the impact of cell viability and density on the primary recovery of monoclonal antibodies
Wohlenberg, O. J., Kortmann, C., Meyer, K. V., Scheper, T. & Solle, D., 2 Feb 2023, In: Engineering in life sciences. 23, 2, e202200056.Research output: Contribution to journal › Article › Research › peer review
2022
- Published
A 3D-printed microfluidic gradient generator with integrated photonic silicon sensors for rapid antimicrobial susceptibility testing
Heuer, C., Preuss, J. A., Buttkewitz, M., Scheper, T., Segal, E. & Bahnemann, J., 22 Nov 2022, In: LAB on a chip. 22, 24, p. 4950-4961 12 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Peripheral blood derived endothelial colony forming cells as suitable cell source for pre-endothelialization of arterial vascular grafts under dynamic flow conditions
Kraus, X., van de Flierdt, E., Renzelmann, J., Thoms, S., Witt, M., Scheper, T. & Blume, C., Sept 2022, In: Microvascular research. 143, 104402.Research output: Contribution to journal › Article › Research › peer review
- Published
Optimization of a mAb production process with regard to robustness and product quality using quality by design principles
Wohlenberg, O. J., Kortmann, C., Meyer, K. V., Schellenberg, J., Dahlmann, K., Bahnemann, J., Scheper, T. & Solle, D., Jul 2022, In: Engineering in life sciences. 22, 7, p. 484-494 11 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Green Synthesis of Silver Nanoparticles Using Hypericum perforatum L. Aqueous Extract with the Evaluation of Its Antibacterial Activity against Clinical and Food Pathogens
Alahmad, A., Al-Zereini, W. A., Hijazin, T. J., Al-Madanat, O. Y., Alghoraibi, I., Al-Qaralleh, O., Al-Qaraleh, S., Feldhoff, A., Walter, J. G. & Scheper, T., May 2022, In: Pharmaceutics. 14, 5, 19 p., 1104.Research output: Contribution to journal › Article › Research › peer review
- Published
Stress-induced increase of monoclonal antibody production in CHO cells
Schellenberg, J., Nagraik, T., Wohlenberg, O. J., Ruhl, S., Bahnemann, J., Scheper, T. & Solle, D., May 2022, In: Engineering in life sciences. 22, 5, p. 427-436 10 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Identification of Major Constituents of Hypericum perforatum L. Extracts in Syria by Development of a Rapid, Simple, and Reproducible HPLC-ESI-Q-TOF MS Analysis and Their Antioxidant Activities
Alahmad, A., Alghoraibi, I., Zein, R., Kraft, S., Dräger, G., Walter, J. G. & Scheper, T., 26 Apr 2022, In: ACS Omega. 7, 16, p. 13475-13493 19 p.Research output: Contribution to journal › Article › Research › peer review
- Published
On-Line Monitoring of Biological Parameters in Microalgal Bioprocesses Using Optical Methods
Havlik, I., Beutel, S., Scheper, T. & Reardon, K. F., 25 Jan 2022, In: Energies. 15, 3, 875.Research output: Contribution to journal › Review article › Research › peer review
2021
- Published
Paving the Way to Overcome Antifungal Drug Resistance: Current Practices and Novel Developments for Rapid and Reliable Antifungal Susceptibility Testing
Heuer, C., Bahnemann, J., Scheper, T. & Segal, E., 12 Nov 2021, In: Small Methods. 5, 11, 2100713.Research output: Contribution to journal › Review article › Research › peer review
- Published
Porous Silicon-Based Aptasensors: Toward Cancer Protein Biomarker Detection
Arshavsky-Graham, S., Ward, S. J., Massad-Ivanir, N., Scheper, T., Weiss, S. M. & Segal, E., 20 Oct 2021, In: ACS Measurement Science Au. 1, 2, p. 82-94 13 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Vascular Network Formation on Macroporous Polydioxanone Scaffolds
Heene, S., Thoms, S., Kalies, S., Wegner, N., Peppermüller, P., Born, N., Walther, F., Scheper, T. & Blume, C. A., 18 Oct 2021, In: Tissue Engineering - Part A. 27, 19-20, p. 1239-1249 11 p.Research output: Contribution to journal › Article › Research
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Clinical applicability of optogenetic gene regulation
Wichert, N., Witt, M., Blume, C. & Scheper, T., 13 Oct 2021, In: Biotechnology and bioengineering. 118, 11, p. 4168-4185 18 p.Research output: Contribution to journal › Review article › Research › peer review
- Published
Refolding, purification, and characterization of constitutive-active human-Smad8 produced as inclusion bodies in ClearColi® BL21 (DE3)
Segovia-Trinidad, C. L., Quaas, B., Li, Z., Lavrentieva, A., Roger, Y., Scheper, T., Hoffmann, A. & Rinas, U., Aug 2021, In: Protein Expression and Purification. 184, 105878.Research output: Contribution to journal › Article › Research › peer review
- Published
Transferrin-decorated niosomes with integrated inp/zns quantum dots and magnetic iron oxide nanoparticles: Dual targeting and imaging of glioma
Seleci, D. A., Maurer, V., Barlas, F. B., Porsiel, J. C., Temel, B., Ceylan, E., Timur, S., Stahl, F., Scheper, T. & Garnweitner, G., 1 May 2021, In: International Journal of Molecular Sciences. 22, 9, 4556.Research output: Contribution to journal › Article › Research › peer review
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Monitoring cell productivity for the production of recombinant proteins by flow cytometry: An effective application using the cold capture assay
Meyer, K. V., Siller, I. G., Schellenberg, J., Gonzalez Salcedo, A., Solle, D., Matuszczyk, J., Scheper, T. & Bahnemann, J., May 2021, In: Engineering in life sciences. 21, 5, p. 288-293 6 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Implementation of QbD strategies in the inoculum expansion of a mAb production process
Böhl, O. J., Schellenberg, J., Bahnemann, J., Hitzmann, B., Scheper, T. & Solle, D., 2 Mar 2021, In: Engineering in life sciences. 21, 3-4, p. 196-207 12 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Implementing a digital infrastructure for the lab using a central laboratory server and the SiLA2 communication standard
Porr, M., Lange, F., Marquard, D., Niemeyer, L., Lindner, P., Scheper, T. & Beutel, S., 2 Mar 2021, In: Engineering in life sciences. 21, 3-4, p. 208-219 12 p.Research output: Contribution to journal › Article › Research › peer review
- Published
A pre-conditioning protocol of peripheral blood derived endothelial colony forming cells for endothelialization of tissue engineered constructs
Kraus, X., Pflaum, M., Thoms, S., Jonczyk, R., Witt, M., Scheper, T. & Blume, C., Mar 2021, In: Microvascular research. 134, 104107.Research output: Contribution to journal › Article › Research › peer review
- Published
In-vitro application of magnetic hybrid niosomes: Targeted sirna-delivery for enhanced breast cancer therapy
Maurer, V., Altin, S., Seleci, D. A., Zarinwall, A., Temel, B., Vogt, P. M., Strauß, S., Stahl, F., Scheper, T., Bucan, V. & Garnweitner, G., Mar 2021, In: Pharmaceutics. 13, 3, 394.Research output: Contribution to journal › Article › Research › peer review
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Hypericum perforatum L.-mediated green synthesis of silver nanoparticles exhibiting antioxidant and anticancer activities
Alahmad, A., Feldhoff, A., Bigall, N. C., Rusch, P., Scheper, T. & Walter, J. G., 14 Feb 2021, In: Nanomaterials. 11, 2, p. 1-26 26 p., 487.Research output: Contribution to journal › Article › Research › peer review
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Comparative Analysis of Mesenchymal Stem Cell Cultivation in Fetal Calf Serum, Human Serum, and Platelet Lysate in 2D and 3D Systems
Kirsch, H. M., Rach, J., Handke, W., Seltsam, A., Pepelanova, I., Strauß, S., Vogt, P., Scheper, T. & Lavrentieva, A., 15 Jan 2021, In: Frontiers in Bioengineering and Biotechnology. 8, 598389.Research output: Contribution to journal › Article › Research › peer review
2020
- Published
Whole-Cell Production of Patchouli Oil Sesquiterpenes in Escherichia coli: Metabolic Engineering and Fermentation Optimization in Solid-Liquid Phase Partitioning Cultivation
Aguilar, F., Ekramzadeh, K., Scheper, T. & Beutel, S., 22 Dec 2020, In: ACS Omega. 5, 50, p. 32436-32446 11 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Accelerated production of α2,8- and α2,9-linked polysialic acid in recombinant Escherichia coli using high cell density cultivation
Bartling, B., Brüchle, N. C., Rehfeld, J. S., Boßmann, D., Fiebig, T., Litschko, C., Fohrer, J., Gerardy-Schahn, R., Scheper, T. & Beutel, S., Dec 2020, In: Biotechnology Reports. 28, e00562.Research output: Contribution to journal › Article › Research › peer review
- Published
Development of an Aptamer-Based Lateral Flow Assay for the Detection of C-Reactive Protein Using Microarray Technology as a Prescreening Platform
Phung, N. L., Walter, J. G., Jonczyk, R., Seiler, L. K., Scheper, T. & Blume, C., 9 Nov 2020, In: ACS combinatorial science. 22, 11, p. 617-629 13 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Live reporting for hypoxia: Hypoxia sensor–modified mesenchymal stem cells as in vitro reporters
Schmitz, C., Pepelanova, I., Seliktar, D., Potekhina, E., Belousov, V. V., Scheper, T. & Lavrentieva, A., 15 Oct 2020, In: Biotechnology and bioengineering. 117, 11, p. 3265-3276 12 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Antifungal Susceptibility Testing of Aspergillus Niger on Silicon Microwells by Intensity-Based Reflectometric Interference Spectroscopy
Heuer, C., Leonard, H., Nitzan, N., Lavy-Alperovitch, A., Massad-Ivanir, N., Scheper, T. & Segal, E., 9 Oct 2020, In: ACS infectious diseases. 6, 10, p. 2560-2566 7 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Stronger Cytotoxicity for Cancer Cells Than for Fast Proliferating Human Stem Cells by Rationally Designed Dinuclear Complexes
Schwarzbich, S., Horstmann Née Gruschka, C., Simon, J., Siebe, L., Moreth, A., Wiegand, C., Lavrentieva, A., Scheper, T., Stammler, A., Bögge, H., Fischer Von Mollard, G. & Glaser, T., 5 Oct 2020, In: Inorganic chemistry. 59, 19, p. 14464-14477 14 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Bringing IoT to the lab: sila2 and open-source-powered gateway module for integrating legacy devices into the digital laboratory
Porr, M. J., Schwarz, S., Lange, F. H., Niemeyer, L., Hentrop, T., Marquard, D., Lindner, P., Scheper, T. & Beutel, S., Oct 2020, In: HardwareX. 8, e00118.Research output: Contribution to journal › Article › Research › peer review
- Published
Customizable 3D-printed (Co-)cultivation systems for in vitro study of angiogenesis
Siller, I. G., Epping, N. M., Lavrentieva, A., Scheper, T. & Bahnemann, J., 25 Sept 2020, In: MATERIALS. 13, 19, p. 1-17 17 p., 4290.Research output: Contribution to journal › Article › Research › peer review
- Published
Digitalization and Bioprocessing: Promises and Challenges
Scheper, T., Beutel, S., McGuinness, N., Heiden, S., Oldiges, M., Lammers, F. & Reardon, K. F., 1 Sept 2020, Digital Twins: Tools and Concepts for Smart Biomanufacturing. Herwig, C., Pörtner, R. & Möller, J. (eds.). 1 ed. Vol. 176. p. 57-69 13 p. (Advances in biochemical engineering/biotechnology).Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
- Published
Purification of the human fibroblast growth factor 2 using novel animal-component free materials
Bolten, S. N., Knoll, A. S., Li, Z., Gellermann, P., Pepelanova, I., Rinas, U. & Scheper, T., 30 Aug 2020, In: Journal of Chromatography A. 1626, 461367.Research output: Contribution to journal › Article › Research › peer review
- Published
Biotechnologische Produktion von niedermolekularer Polysialinsäure für pharmazeutische Applikationen
Bartling, B., Rehfeld, J. S., Boßmann, D., Scheper, T. & Beutel, S., 28 Aug 2020, In: Chemie Ingenieur Technik. 92, 9, p. 1221 1 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Digital image analysis in the lab of the future
Porr, M. J., Marquard, D., Lange, F. H., Austerjost, J., McVean, K., Hermann, A., Maeß, C., Lindner, P., Scheper, T. & Beutel, S., 28 Aug 2020, In: Chemie Ingenieur Technik. 92, 9, p. 1249 1 p.Research output: Contribution to journal › Meeting Abstract › Research
- Published
Digitalization in industrial biotechnology: Challenges of miniaturization, automation, and interfaces
Hemmerich, J., Osthege, M., Reiter, A., Wiechert, W., Noack, S., Oldiges, M., Marquard, D., Porr, M. J., Lange, F. H., Scheper, T., Scheper, T., Beutel, S., von der Eichen, N., Broming, L. & Weuster-Botz, D., 28 Aug 2020, In: Chemie Ingenieur Technik. 92, 9, p. 1160 1 p.Research output: Contribution to journal › Meeting Abstract › Research
- Published
Aptasensors for point-of-care detection of small molecules
Prante, M., Segal, E., Scheper, T., Bahnemann, J. & Walter, J., 26 Aug 2020, In: Biosensors. 10, 9, 19 p., 108.Research output: Contribution to journal › Review article › Research › peer review