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Publications

  1. 2026
  2. Published

    Nickel: Geochemistry, biochemistry and its role in chemical and biological evolutions

    Neubeck, A. & Kirschning, A., Jan 2026, In: Earth-Science Reviews. 272, 105324.

    Research output: Contribution to journalArticleResearchpeer review

  3. 2025
  4. Published

    Design, Synthesis, and Cytotoxic Evaluation of New Structurally Simplified and Highly Potent Third-Generation Tubulysin Derivatives

    Yadav, K., Kalita, T., Sharma, L., Pandit, A., Pathak, B., Dräger, G., Kirschning, A. & Chelvam, V., 19 Aug 2025, In: Chemistry - a European journal. 31, 46, e01965.

    Research output: Contribution to journalArticleResearchpeer review

  5. Published

    Chemoenzymatic Generation of Thio-analogues of δ-Cadinene, δ-Cadinol, and a Thio-diquinane Using 8-Thio-farnesylpyrophosphate

    Jäger, B., Budde, J. L., Birke, N., Hauke, M. & Kirschning, A., 25 Jul 2025, In: Journal of natural products. 88, 7, p. 1653-1662 10 p.

    Research output: Contribution to journalArticleResearchpeer review

  6. Published

    Reprogramming the Cyclization of the Sesquiterpene Synthase BcBOT2 Using 2,3-Z-Configured FPP Derivatives and by Means of “Methyl Mapping”

    Budde, J. L., Çay, M. Y., Dräger, G., Droste, J., Hassanin, A., Davari, M. D. & Kirschning, A., 16 May 2025, In: ACS catalysis. 15, 10, p. 8125-8139 15 p.

    Research output: Contribution to journalArticleResearchpeer review

  7. Published

    Expanding the “Terpenome”: Diterpene Synthases Accept GGPP-Ether Substrates

    Ravkina, V., Dräger, G., Droste, J., Schwörer, S., Hassanin, A., Davari, M. D. & Kirschning, A., 2 May 2025, In: ACS catalysis. 15, 9, p. 6796-6811 16 p.

    Research output: Contribution to journalArticleResearchpeer review

  8. Published

    Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus

    Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M. & Kirschning, A., 12 Mar 2025, In: Nature Communications. 16, 1, 13 p., 2464.

    Research output: Contribution to journalArticleResearchpeer review

  9. Published

    Zika virus modulates human fibroblasts to enhance transmission success in a controlled lab-setting

    Mozūraitis, R., Cirksena, K., Raftari, M., Hajkazemian, M., Mustapha Abiodun, M., Brahimi, J., Radžiutė, S., Apšegaitė, V., Bernotienė, R., Ignatowicz, L., Hick, T., Kirschning, A., Lenman, A., Gerold, G. & Emami, S. N., 30 Jan 2025, In: Communications Biology. 8, 1, 14 p., 139.

    Research output: Contribution to journalArticleResearchpeer review

  10. Published

    Expanding the “Terpenome”: Applications of Unspecific Peroxygenases (UPOs) in Oxidations of Unnatural Terpenoids

    Struwe, H., Grimm, C., Dräger, G., Beutel, S., Alcalde, M., Kirschning, A. & Kara, S., 9 Jan 2025, In: CHEMCATCHEM. 17, 1, e202401414.

    Research output: Contribution to journalArticleResearchpeer review

  11. Published

    Chemoenzymatic Formation of Oxa-Terpenoids by Sesqui- and Diterpene Synthase-Mediated Biotransformations with 9-Oxy-FPP Ether Derivatives

    Struwe, H., Nguyen, T., Schwörer, S., Droste, J., Spinck, H. & Kirschning, A., 2025, In: Biochemistry. 64, 2, p. 498–508 11 p.

    Research output: Contribution to journalArticleResearchpeer review

  12. Published

    The “factory in a lab”: telescoping the Matteson and Matteson-Hoppe-Aggarwal boronate chemistry under flow conditions

    Fricke, F., Dräger, G. & Kirschning, A., 2025, In: Reaction Chemistry and Engineering. 10, 5, p. 1048-1053 6 p.

    Research output: Contribution to journalArticleResearchpeer review

  13. 2024
  14. Published

    Synthetic studies on the tetrasubstituted D-ring of cystobactamids lead to potent terephthalic acid antibiotics

    Stappert, M., Kohnhäuser, D., Seedorf, T., Coetzee, J., Rox, K., Fuchs, H. L. S., Cirnski, K., Leitner, C., Herrmann, J., Kirschning, A., Müller, R. & Brönstrup, M., 5 Nov 2024, In: Communications Chemistry. 7, 1, 252.

    Research output: Contribution to journalArticleResearchpeer review

  15. Published

    Optimization of the Central α-Amino Acid in Cystobactamids to the Broad-Spectrum, Resistance-Breaking Antibiotic CN-CC-861

    Kohnhäuser, D., Seedorf, T., Cirnski, K., Heimann, D., Coetzee, J., Sordello, S., Richter, J., Stappert, M., Sabuco, J. F., Corbett, D., Bacque, E., Rox, K., Herrmann, J., Vassort, A., Muller, R., Kirschning, A. & Bronstrup, M., 10 Oct 2024, In: Journal of medicinal chemistry. 67, 19, p. 17162-17190 29 p.

    Research output: Contribution to journalArticleResearchpeer review

  16. Published

    Telescoping a Prenyltransferase and a Diterpene Synthase to Transform Unnatural FPP Derivatives to Diterpenoids

    Struwe, H., Li, H., Schrödter, F., Höft, L., Fohrer, J., Dickschat, J. S. & Kirschning, A., 19 Jul 2024, In: Organic letters. 26, 28, p. 5888-5892 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  17. Published

    Sesquiterpene Cyclase BcBOT2 Promotes the Unprecedented Wagner-Meerwein Rearrangement of the Methoxy Group

    Moeller, M., Dhar, D., Dräger, G., Özbasi, M., Struwe, H., Wildhagen, M., Davari, M. D., Beutel, S. & Kirschning, A., 3 Jul 2024, In: Journal of the American Chemical Society. 146, 26, p. 17838-17846 9 p.

    Research output: Contribution to journalArticleResearchpeer review

  18. Published

    Dextrans, Pullulan and Lentinan, New Scaffold Materials for Use as Hydrogels in Tissue Engineering

    Lienig, P., Banerjee, S., Kenneweg, F., Thum, T., Kirschning, A. & Dräger, G., 16 Apr 2024, In: Chemistry - a European journal. 30, 22, 12 p., e202303843.

    Research output: Contribution to journalArticleResearchpeer review

  19. Published

    Is Simultaneous Binding to DNA and Gyrase Important for the Antibacterial Activity of Cystobactamids?

    Solga, D., Wieske, L. H. E., Wilcox, S., Zeilinger, C., Jansen-Olliges, L., Cirnski, K., Herrmann, J., Müller, R., Erdelyi, M. & Kirschning, A., 5 Apr 2024, In: Chemistry - a European journal. 30, 19, 14 p., e202303796.

    Research output: Contribution to journalArticleResearchpeer review

  20. Published

    Evolution at the Origins of Life?

    Schoenmakers, L. L. J., Reydon, T. A. C. & Kirschning, A., 24 Jan 2024, In: Life. 14, 2, 24 p., 175.

    Research output: Contribution to journalReview articleResearchpeer review

  21. Published

    Halogenated Rocaglate Derivatives: Pan-antiviral Agents against Hepatitis E Virus and Emerging Viruses

    Victoria, C., Schulz, G., Klöhn, M., Weber, S., Holicki, C. M., Brüggemann, Y., Becker, M., Gerold, G., Eiden, M., Groschup, M. H., Steinmann, E. & Kirschning, A., 11 Jan 2024, In: Journal of medicinal chemistry. 67, 1, p. 289-321 33 p.

    Research output: Contribution to journalArticleResearchpeer review

  22. Published

    Chemoenzymatic Synthesis of a New Germacrene Derivative Named Germacrene F

    Struwe, H., Droste, J., Dhar, D., Davari, M. D. & Kirschning, A., 2 Jan 2024, In: CHEMBIOCHEM. 25, 1, 6 p., e202300599.

    Research output: Contribution to journalArticleResearchpeer review

  23. Published

    [4+1] Cyclizations to Enantiopure Multifunctional Cyclopentanes from d -Glucose Using Formyl Dianion Synthons

    Kirschning, A., Schaumann, E., Bräuer, N., Michel, T. & Oelze, S., 2024, In: SYNLETT. 35, 9, p. 973-978 6 p.

    Research output: Contribution to journalArticleResearchpeer review

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