Details
| Translated title of the contribution | Safety of folic acid: Facts and fictions |
|---|---|
| Original language | German |
| Pages (from-to) | 297-306 |
| Number of pages | 10 |
| Journal | Medizinische Monatsschrift fur Pharmazeuten |
| Volume | 38 |
| Issue number | 8 |
| Publication status | Published - 1 Aug 2015 |
Abstract
Improving dietary folate intake is a central public health goal. However, critical voices have become louder warning of too high intake of folic acid. Safety concerns of a high folic acid exposure are usually limited to synthetic folic acid contained in drugs and food supplements. Against this background, the present article focuses on two matters: (a) How do the absorption and metabolism of synthetic folic acid differ from that of other folates? (b) How has the longterm safety of folic acid to be judged, especially regarding the risk of colorectal cancer, autism, asthma, impaired immune defence, masking vitamin B12 deficiency and interactions with the methotrexate metabolism?.
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In: Medizinische Monatsschrift fur Pharmazeuten, Vol. 38, No. 8, 01.08.2015, p. 297-306.
Research output: Contribution to journal › Article › Research
}
TY - JOUR
T1 - Sicherheit von Folsäure. Fakten und Fiktionen
AU - Ströhle, A.
AU - Wolters, Maike
AU - Hahn, A.
N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Improving dietary folate intake is a central public health goal. However, critical voices have become louder warning of too high intake of folic acid. Safety concerns of a high folic acid exposure are usually limited to synthetic folic acid contained in drugs and food supplements. Against this background, the present article focuses on two matters: (a) How do the absorption and metabolism of synthetic folic acid differ from that of other folates? (b) How has the longterm safety of folic acid to be judged, especially regarding the risk of colorectal cancer, autism, asthma, impaired immune defence, masking vitamin B12 deficiency and interactions with the methotrexate metabolism?.
AB - Improving dietary folate intake is a central public health goal. However, critical voices have become louder warning of too high intake of folic acid. Safety concerns of a high folic acid exposure are usually limited to synthetic folic acid contained in drugs and food supplements. Against this background, the present article focuses on two matters: (a) How do the absorption and metabolism of synthetic folic acid differ from that of other folates? (b) How has the longterm safety of folic acid to be judged, especially regarding the risk of colorectal cancer, autism, asthma, impaired immune defence, masking vitamin B12 deficiency and interactions with the methotrexate metabolism?.
UR - http://www.scopus.com/inward/record.url?scp=84938577056&partnerID=8YFLogxK
M3 - Artikel
VL - 38
SP - 297
EP - 306
JO - Medizinische Monatsschrift fur Pharmazeuten
JF - Medizinische Monatsschrift fur Pharmazeuten
SN - 0342-9601
IS - 8
ER -