Optimierung der laserparameter für die intrastromale schnittführung mittels ultrakurzer laserpulse

Research output: Contribution to journalArticleResearchpeer review

Authors

  • A. Heisterkamp
  • T. Ripken
  • E. Lütkefles
  • W. Drommer
  • H. Lubatschowski
  • H. Welling
  • W. Ertmer

Research Organisations

External Research Organisations

  • Laser Zentrum Hannover e.V. (LZH)
  • University of Veterinary Medicine of Hannover, Foundation
View graph of relations

Details

Translated title of the contributionOptimisation of the laser parameters for intrastromal incisions using ultrashort laser pulses
Original languageGerman
Pages (from-to)623-628
Number of pages6
JournalOPHTHALMOLOGE
Volume98
Issue number7
Publication statusPublished - 16 Aug 2001

Abstract

Background: With the assistance of ultrashort laser pulses (ca. 200 fs pulse duration) it is possible to perform precise incisions inside the corneal stroma with a width of a few microns. The advantage of ultrashort pulses is that the required energy of a few microjoules is more than an order of magnitude lower compared with longer pulse durations, i.e. ps or ns pulses. Therefore, the secondary effects, such as thermal and mechanical damage to the surrounding tissue and the amount of radiation reaching the retina, are reduced. This method of intrastromal photodisruption allows a very well defined deposition of energy within the laser focus inside the corneal stroma, accompanied by minimal collateral damage. Methods: The possibilities of performing intrastromal cuts using fs-laser pulses at a wavelength of 780 nm and pulse durations of 200 fs were studied using a titanium-sapphire laser system. The treated tissue samples were analysed by light and scanning electron microscopy to determine incision quality, reproducibility and achievable accuracy. The mechanical side effects of fs-photodisruption inside the surrounding tissue were analysed by pressure measurements using pyroelectric transducers. Conclusion: The thermal and mechanical side-effects of this method are very low and comparable to the effects during excimer treatment. Therefore an application of ultrashort laser pulses in refractive surgery appears to be a feasible alternative.

ASJC Scopus subject areas

Cite this

Optimierung der laserparameter für die intrastromale schnittführung mittels ultrakurzer laserpulse. / Heisterkamp, A.; Ripken, T.; Lütkefles, E. et al.
In: OPHTHALMOLOGE, Vol. 98, No. 7, 16.08.2001, p. 623-628.

Research output: Contribution to journalArticleResearchpeer review

Heisterkamp, A, Ripken, T, Lütkefles, E, Drommer, W, Lubatschowski, H, Welling, H & Ertmer, W 2001, 'Optimierung der laserparameter für die intrastromale schnittführung mittels ultrakurzer laserpulse', OPHTHALMOLOGE, vol. 98, no. 7, pp. 623-628. https://doi.org/10.1007/s003470170097
Heisterkamp, A., Ripken, T., Lütkefles, E., Drommer, W., Lubatschowski, H., Welling, H., & Ertmer, W. (2001). Optimierung der laserparameter für die intrastromale schnittführung mittels ultrakurzer laserpulse. OPHTHALMOLOGE, 98(7), 623-628. https://doi.org/10.1007/s003470170097
Heisterkamp A, Ripken T, Lütkefles E, Drommer W, Lubatschowski H, Welling H et al. Optimierung der laserparameter für die intrastromale schnittführung mittels ultrakurzer laserpulse. OPHTHALMOLOGE. 2001 Aug 16;98(7):623-628. doi: 10.1007/s003470170097
Heisterkamp, A. ; Ripken, T. ; Lütkefles, E. et al. / Optimierung der laserparameter für die intrastromale schnittführung mittels ultrakurzer laserpulse. In: OPHTHALMOLOGE. 2001 ; Vol. 98, No. 7. pp. 623-628.
Download
@article{35051ba8cc6a46babc4d7d8ef8360653,
title = "Optimierung der laserparameter f{\"u}r die intrastromale schnittf{\"u}hrung mittels ultrakurzer laserpulse",
abstract = "Background: With the assistance of ultrashort laser pulses (ca. 200 fs pulse duration) it is possible to perform precise incisions inside the corneal stroma with a width of a few microns. The advantage of ultrashort pulses is that the required energy of a few microjoules is more than an order of magnitude lower compared with longer pulse durations, i.e. ps or ns pulses. Therefore, the secondary effects, such as thermal and mechanical damage to the surrounding tissue and the amount of radiation reaching the retina, are reduced. This method of intrastromal photodisruption allows a very well defined deposition of energy within the laser focus inside the corneal stroma, accompanied by minimal collateral damage. Methods: The possibilities of performing intrastromal cuts using fs-laser pulses at a wavelength of 780 nm and pulse durations of 200 fs were studied using a titanium-sapphire laser system. The treated tissue samples were analysed by light and scanning electron microscopy to determine incision quality, reproducibility and achievable accuracy. The mechanical side effects of fs-photodisruption inside the surrounding tissue were analysed by pressure measurements using pyroelectric transducers. Conclusion: The thermal and mechanical side-effects of this method are very low and comparable to the effects during excimer treatment. Therefore an application of ultrashort laser pulses in refractive surgery appears to be a feasible alternative.",
keywords = "Intrastromal, Photodisruption, Refractive surgery, Ultrashort laser pulses",
author = "A. Heisterkamp and T. Ripken and E. L{\"u}tkefles and W. Drommer and H. Lubatschowski and H. Welling and W. Ertmer",
year = "2001",
month = aug,
day = "16",
doi = "10.1007/s003470170097",
language = "Deutsch",
volume = "98",
pages = "623--628",
journal = "OPHTHALMOLOGE",
issn = "0941-293X",
publisher = "Springer Verlag",
number = "7",

}

Download

TY - JOUR

T1 - Optimierung der laserparameter für die intrastromale schnittführung mittels ultrakurzer laserpulse

AU - Heisterkamp, A.

AU - Ripken, T.

AU - Lütkefles, E.

AU - Drommer, W.

AU - Lubatschowski, H.

AU - Welling, H.

AU - Ertmer, W.

PY - 2001/8/16

Y1 - 2001/8/16

N2 - Background: With the assistance of ultrashort laser pulses (ca. 200 fs pulse duration) it is possible to perform precise incisions inside the corneal stroma with a width of a few microns. The advantage of ultrashort pulses is that the required energy of a few microjoules is more than an order of magnitude lower compared with longer pulse durations, i.e. ps or ns pulses. Therefore, the secondary effects, such as thermal and mechanical damage to the surrounding tissue and the amount of radiation reaching the retina, are reduced. This method of intrastromal photodisruption allows a very well defined deposition of energy within the laser focus inside the corneal stroma, accompanied by minimal collateral damage. Methods: The possibilities of performing intrastromal cuts using fs-laser pulses at a wavelength of 780 nm and pulse durations of 200 fs were studied using a titanium-sapphire laser system. The treated tissue samples were analysed by light and scanning electron microscopy to determine incision quality, reproducibility and achievable accuracy. The mechanical side effects of fs-photodisruption inside the surrounding tissue were analysed by pressure measurements using pyroelectric transducers. Conclusion: The thermal and mechanical side-effects of this method are very low and comparable to the effects during excimer treatment. Therefore an application of ultrashort laser pulses in refractive surgery appears to be a feasible alternative.

AB - Background: With the assistance of ultrashort laser pulses (ca. 200 fs pulse duration) it is possible to perform precise incisions inside the corneal stroma with a width of a few microns. The advantage of ultrashort pulses is that the required energy of a few microjoules is more than an order of magnitude lower compared with longer pulse durations, i.e. ps or ns pulses. Therefore, the secondary effects, such as thermal and mechanical damage to the surrounding tissue and the amount of radiation reaching the retina, are reduced. This method of intrastromal photodisruption allows a very well defined deposition of energy within the laser focus inside the corneal stroma, accompanied by minimal collateral damage. Methods: The possibilities of performing intrastromal cuts using fs-laser pulses at a wavelength of 780 nm and pulse durations of 200 fs were studied using a titanium-sapphire laser system. The treated tissue samples were analysed by light and scanning electron microscopy to determine incision quality, reproducibility and achievable accuracy. The mechanical side effects of fs-photodisruption inside the surrounding tissue were analysed by pressure measurements using pyroelectric transducers. Conclusion: The thermal and mechanical side-effects of this method are very low and comparable to the effects during excimer treatment. Therefore an application of ultrashort laser pulses in refractive surgery appears to be a feasible alternative.

KW - Intrastromal

KW - Photodisruption

KW - Refractive surgery

KW - Ultrashort laser pulses

UR - http://www.scopus.com/inward/record.url?scp=0034903911&partnerID=8YFLogxK

U2 - 10.1007/s003470170097

DO - 10.1007/s003470170097

M3 - Artikel

C2 - 11490739

AN - SCOPUS:0034903911

VL - 98

SP - 623

EP - 628

JO - OPHTHALMOLOGE

JF - OPHTHALMOLOGE

SN - 0941-293X

IS - 7

ER -