Omega-3 world map: 2024 update

Research output: Contribution to journalReview articleResearchpeer review

Authors

External Research Organisations

  • Fatty Acid Research Institute (FARI)
  • University of Ottawa
  • Global Organization for EPA and DHA Omega-3s (GOED)
  • University of Waterloo
  • University of South Dakota
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Details

Original languageEnglish
Article number101286
JournalProgress in lipid research
Volume95
Early online date13 Jun 2024
Publication statusPublished - Jul 2024

Abstract

In 2016, the first worldwide n3 PUFA status map was published using the Omega-3 Index (O3I) as standard biomarker. The O3I is defined as the percentage of EPA + DHA in red blood cell (RBC) membrane FAs. The purpose of the present study was to update the 2016 map with new data. In order to be included, studies had to report O3I and/or blood EPA + DHA levels in metrics convertible into an estimated O3I, in samples drawn after 1999. To convert the non-RBC-based EPA + DHA metrics into RBC we used newly developed equations. Baseline data from clinical trials and observational studies were acceptable. A literature search identified 328 studies meeting inclusion criteria encompassing 342,864 subjects from 48 countries/regions. Weighted mean country O3I levels were categorized into very low ≤4%, low >4-6%, moderate >6-8%, and desirable >8%. We found that the O3I in most countries was low to very low. Notable differences between the current and 2016 map were 1) USA, Canada, Italy, Turkey, UK, Ireland and Greece (moving from the very low to low category); 2) France, Spain and New Zealand (low to moderate); and 3) Finland and Iceland (moderate to desirable). Countries such as Iran, Egypt, and India exhibited particularly poor O3I levels.

Keywords

    Conversion equation, DHA, EPA, Estimated Omega-3 Index, Global omega-3 status, GOED clinical database

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Cell Biology

Cite this

Omega-3 world map: 2024 update. / Schuchardt, Jan Philipp; Beinhorn, Philine; Hu, Xue Feng et al.
In: Progress in lipid research, Vol. 95, 101286, 07.2024.

Research output: Contribution to journalReview articleResearchpeer review

Schuchardt, JP, Beinhorn, P, Hu, XF, Chan, HM, Roke, K, Bernasconi, A, Hahn, A, Sala-Vila, A, Stark, KD & Harris, WS 2024, 'Omega-3 world map: 2024 update', Progress in lipid research, vol. 95, 101286. https://doi.org/10.1016/j.plipres.2024.101286
Schuchardt, J. P., Beinhorn, P., Hu, X. F., Chan, H. M., Roke, K., Bernasconi, A., Hahn, A., Sala-Vila, A., Stark, K. D., & Harris, W. S. (2024). Omega-3 world map: 2024 update. Progress in lipid research, 95, Article 101286. https://doi.org/10.1016/j.plipres.2024.101286
Schuchardt JP, Beinhorn P, Hu XF, Chan HM, Roke K, Bernasconi A et al. Omega-3 world map: 2024 update. Progress in lipid research. 2024 Jul;95:101286. Epub 2024 Jun 13. doi: 10.1016/j.plipres.2024.101286
Schuchardt, Jan Philipp ; Beinhorn, Philine ; Hu, Xue Feng et al. / Omega-3 world map : 2024 update. In: Progress in lipid research. 2024 ; Vol. 95.
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AU - Beinhorn, Philine

AU - Hu, Xue Feng

AU - Chan, Hing Man

AU - Roke, Kaitlin

AU - Bernasconi, Aldo

AU - Hahn, Andreas

AU - Sala-Vila, Aleix

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