Details
Original language | English |
---|---|
Pages (from-to) | 432-439 |
Number of pages | 8 |
Journal | The British journal of nutrition |
Volume | 125 |
Issue number | 4 |
Early online date | 23 Jul 2020 |
Publication status | Published - 28 Feb 2021 |
Abstract
The n-3 PUFA, EPA and DHA, play an important role in human health. As the intake of EPA and DHA from the diet is often inadequate, supplementation of those fatty acids is recommended. A novel source of n-3 PUFA is Calanus finmarchicus oil (CO) which contains fatty acids mainly bound in wax esters. To date, no data are available on the effects of long-Term intake of this marine oil on n-3 PUFA blood levels. Therefore, the aim of this study was to evaluate the effect of CO on the n-3 PUFA blood levels using the omega-3 index (O3I). The data originate from a larger randomised controlled trial. For this analysis, samples from seventy-Two participants (59·2 (sd 6·2) years, BMI 27·7 (sd 5·28) kg/m2) were analysed. Of those, thirty-six performed 2×/week exercise and received 2 g of CO, which provided 124 mg stearidonic acid (SDA), 109 mg EPA and 87 mg DHA daily (EXCO group), while the other group performed exercise only (EX group) and served as a control for this analysis. The O3I increased from 6·07 (sd 1·29) % at baseline to 7·37 (sd 1·10) % after 12 weeks within the EXCO group (P < 0·001), while there were no significant changes in the EX group (6·01 (sd 1·26)-6·15 (sd 1·32) %, P = 0·238). These data provide first evidence that wax ester-bound n-3 PUFA from CO can significantly increase the O3I despite relatively low EPA + DHA amounts. Further, the effects of exercise could be excluded.
Keywords
- DHA, EPA, marine oil, polyunsaturated fatty acids, wax ester, PUFA, Marine oil, Wax esters
ASJC Scopus subject areas
- Nursing(all)
- Nutrition and Dietetics
- Medicine(all)
- Medicine (miscellaneous)
Sustainable Development Goals
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In: The British journal of nutrition, Vol. 125, No. 4, 28.02.2021, p. 432-439.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Intake of Calanus finmarchicus oil for 12 weeks improves omega-3 index in healthy older subjects engaging in an exercise programme
AU - Wasserfurth, Paulina
AU - Nebl, Josefine
AU - Boßlau, Tim Konstantin
AU - Krüger, Karsten
AU - Hahn, Andreas
AU - Schuchardt, Jan Philipp
N1 - Funding Information: First of all, the authors would like to thank all participants who took part in our study, and the fitness centres that supported the implementation of this study. Further, the authors thank Calanus AS for providing the CO capsules, Heike Kohrs for technical assistance and Dr Erinn Gideons for proofreading our manuscript. This research received no external financial support.
PY - 2021/2/28
Y1 - 2021/2/28
N2 - The n-3 PUFA, EPA and DHA, play an important role in human health. As the intake of EPA and DHA from the diet is often inadequate, supplementation of those fatty acids is recommended. A novel source of n-3 PUFA is Calanus finmarchicus oil (CO) which contains fatty acids mainly bound in wax esters. To date, no data are available on the effects of long-Term intake of this marine oil on n-3 PUFA blood levels. Therefore, the aim of this study was to evaluate the effect of CO on the n-3 PUFA blood levels using the omega-3 index (O3I). The data originate from a larger randomised controlled trial. For this analysis, samples from seventy-Two participants (59·2 (sd 6·2) years, BMI 27·7 (sd 5·28) kg/m2) were analysed. Of those, thirty-six performed 2×/week exercise and received 2 g of CO, which provided 124 mg stearidonic acid (SDA), 109 mg EPA and 87 mg DHA daily (EXCO group), while the other group performed exercise only (EX group) and served as a control for this analysis. The O3I increased from 6·07 (sd 1·29) % at baseline to 7·37 (sd 1·10) % after 12 weeks within the EXCO group (P < 0·001), while there were no significant changes in the EX group (6·01 (sd 1·26)-6·15 (sd 1·32) %, P = 0·238). These data provide first evidence that wax ester-bound n-3 PUFA from CO can significantly increase the O3I despite relatively low EPA + DHA amounts. Further, the effects of exercise could be excluded.
AB - The n-3 PUFA, EPA and DHA, play an important role in human health. As the intake of EPA and DHA from the diet is often inadequate, supplementation of those fatty acids is recommended. A novel source of n-3 PUFA is Calanus finmarchicus oil (CO) which contains fatty acids mainly bound in wax esters. To date, no data are available on the effects of long-Term intake of this marine oil on n-3 PUFA blood levels. Therefore, the aim of this study was to evaluate the effect of CO on the n-3 PUFA blood levels using the omega-3 index (O3I). The data originate from a larger randomised controlled trial. For this analysis, samples from seventy-Two participants (59·2 (sd 6·2) years, BMI 27·7 (sd 5·28) kg/m2) were analysed. Of those, thirty-six performed 2×/week exercise and received 2 g of CO, which provided 124 mg stearidonic acid (SDA), 109 mg EPA and 87 mg DHA daily (EXCO group), while the other group performed exercise only (EX group) and served as a control for this analysis. The O3I increased from 6·07 (sd 1·29) % at baseline to 7·37 (sd 1·10) % after 12 weeks within the EXCO group (P < 0·001), while there were no significant changes in the EX group (6·01 (sd 1·26)-6·15 (sd 1·32) %, P = 0·238). These data provide first evidence that wax ester-bound n-3 PUFA from CO can significantly increase the O3I despite relatively low EPA + DHA amounts. Further, the effects of exercise could be excluded.
KW - DHA
KW - EPA
KW - marine oil
KW - polyunsaturated fatty acids
KW - wax ester
KW - PUFA
KW - Marine oil
KW - Wax esters
UR - http://www.scopus.com/inward/record.url?scp=85089357300&partnerID=8YFLogxK
U2 - 10.1017/S0007114520002809
DO - 10.1017/S0007114520002809
M3 - Article
C2 - 32698912
VL - 125
SP - 432
EP - 439
JO - The British journal of nutrition
JF - The British journal of nutrition
SN - 0007-1145
IS - 4
ER -