Details
| Original language | English |
|---|---|
| Pages (from-to) | 817-825 |
| Number of pages | 9 |
| Journal | European Journal of Applied Physiology |
| Volume | 121 |
| Issue number | 3 |
| Early online date | 23 Dec 2020 |
| Publication status | Published - Mar 2021 |
| Externally published | Yes |
Abstract
Purpose: To test the hypothesis that the combination of endurance training and hypoxia leads to greater improvements in resting and exercise blood pressure in old sedentary individuals compared to endurance training only. Methods: We randomly assigned 29 old overweight participants (age: 62 ± 6 years, body mass index (BMI): 28.5 ± 0.5 kg/m2, 52% men) to single blind 8-week bicycle exercise in hypoxia (fraction of inspired oxygen (FIO2) = 0.15) or normoxia (FIO2 = 0.21). Brachial blood pressure was measured at rest, during maximal incremental exercise testing, and during a 30 min constant work rate test, at baseline and after the training period. Results: Work rate, heart rate and perceived exertion during training were similar in both groups, with lower oxygen saturation for participants exercising under hypoxia (88.7 ± 1.5 vs. 96.2 ± 1.2%, t(27) = − 13.04, p < 0.001, |g|= 4.85). Office blood pressure and blood pressure during incremental exercise tests did not change significantly in either group after the training program. Systolic blood pressure during the constant work rate test was reduced after training in hypoxia (160 ± 18 vs. 151 ± 14 mmHg, t(13) = 2.44 p < 0.05, |d|= 0.55) but not normoxia (154 ± 22 vs. 150 ± 16 mmHg, t(14) = 0.75, p = 0.46, |d|= 0.18) with no difference between groups over time (F = 0.08, p = 0.77, η2 = 0.01). Conclusion: In old individuals hypoxia in addition to exercise does not have superior effects on office or exercise blood pressure compared to training in normoxia. Trial registration number: ClinicalTrials.gov No. NCT02196623 (registered 22 July 2014).
Keywords
- Blood pressure, Elderly, Exercise, Hypoxia
ASJC Scopus subject areas
- Medicine(all)
- Orthopedics and Sports Medicine
- Medicine(all)
- Public Health, Environmental and Occupational Health
- Medicine(all)
- Physiology (medical)
Sustainable Development Goals
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In: European Journal of Applied Physiology, Vol. 121, No. 3, 03.2021, p. 817-825.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Effect of normobaric hypoxic exercise on blood pressure in old individuals
AU - Hein, Markus
AU - Chobanyan-Jürgens, Kristine
AU - Tegtbur, Uwe
AU - Engeli, Stefan
AU - Jordan, Jens
AU - Haufe, Sven
N1 - Funding Information: Open Access funding enabled and organized by Projekt DEAL. This work was supported by a Grant from the German Research Foundation (Reference No. HA 7037/ 2-1) to SH.
PY - 2021/3
Y1 - 2021/3
N2 - Purpose: To test the hypothesis that the combination of endurance training and hypoxia leads to greater improvements in resting and exercise blood pressure in old sedentary individuals compared to endurance training only. Methods: We randomly assigned 29 old overweight participants (age: 62 ± 6 years, body mass index (BMI): 28.5 ± 0.5 kg/m2, 52% men) to single blind 8-week bicycle exercise in hypoxia (fraction of inspired oxygen (FIO2) = 0.15) or normoxia (FIO2 = 0.21). Brachial blood pressure was measured at rest, during maximal incremental exercise testing, and during a 30 min constant work rate test, at baseline and after the training period. Results: Work rate, heart rate and perceived exertion during training were similar in both groups, with lower oxygen saturation for participants exercising under hypoxia (88.7 ± 1.5 vs. 96.2 ± 1.2%, t(27) = − 13.04, p < 0.001, |g|= 4.85). Office blood pressure and blood pressure during incremental exercise tests did not change significantly in either group after the training program. Systolic blood pressure during the constant work rate test was reduced after training in hypoxia (160 ± 18 vs. 151 ± 14 mmHg, t(13) = 2.44 p < 0.05, |d|= 0.55) but not normoxia (154 ± 22 vs. 150 ± 16 mmHg, t(14) = 0.75, p = 0.46, |d|= 0.18) with no difference between groups over time (F = 0.08, p = 0.77, η2 = 0.01). Conclusion: In old individuals hypoxia in addition to exercise does not have superior effects on office or exercise blood pressure compared to training in normoxia. Trial registration number: ClinicalTrials.gov No. NCT02196623 (registered 22 July 2014).
AB - Purpose: To test the hypothesis that the combination of endurance training and hypoxia leads to greater improvements in resting and exercise blood pressure in old sedentary individuals compared to endurance training only. Methods: We randomly assigned 29 old overweight participants (age: 62 ± 6 years, body mass index (BMI): 28.5 ± 0.5 kg/m2, 52% men) to single blind 8-week bicycle exercise in hypoxia (fraction of inspired oxygen (FIO2) = 0.15) or normoxia (FIO2 = 0.21). Brachial blood pressure was measured at rest, during maximal incremental exercise testing, and during a 30 min constant work rate test, at baseline and after the training period. Results: Work rate, heart rate and perceived exertion during training were similar in both groups, with lower oxygen saturation for participants exercising under hypoxia (88.7 ± 1.5 vs. 96.2 ± 1.2%, t(27) = − 13.04, p < 0.001, |g|= 4.85). Office blood pressure and blood pressure during incremental exercise tests did not change significantly in either group after the training program. Systolic blood pressure during the constant work rate test was reduced after training in hypoxia (160 ± 18 vs. 151 ± 14 mmHg, t(13) = 2.44 p < 0.05, |d|= 0.55) but not normoxia (154 ± 22 vs. 150 ± 16 mmHg, t(14) = 0.75, p = 0.46, |d|= 0.18) with no difference between groups over time (F = 0.08, p = 0.77, η2 = 0.01). Conclusion: In old individuals hypoxia in addition to exercise does not have superior effects on office or exercise blood pressure compared to training in normoxia. Trial registration number: ClinicalTrials.gov No. NCT02196623 (registered 22 July 2014).
KW - Blood pressure
KW - Elderly
KW - Exercise
KW - Hypoxia
UR - http://www.scopus.com/inward/record.url?scp=85099516243&partnerID=8YFLogxK
U2 - 10.1007/s00421-020-04572-6
DO - 10.1007/s00421-020-04572-6
M3 - Article
C2 - 33355713
AN - SCOPUS:85099516243
VL - 121
SP - 817
EP - 825
JO - European Journal of Applied Physiology
JF - European Journal of Applied Physiology
SN - 1439-6319
IS - 3
ER -