Details
| Original language | English |
|---|---|
| Pages (from-to) | 2009-2013 |
| Number of pages | 5 |
| Journal | Synlett |
| Issue number | 13 |
| Publication status | Published - 9 Jul 2010 |
Abstract
Inductively heated copper wire inside a flow microreactor can serve as a source for a catalytic copper species that promotes 1,3-dipolar cycloadditions of alkynes with in situ formed azides to yield 1,2,3-triazoles. The same setup was used to carry out decarboxylations of 2-alkynoic acids and for the intramolecular C-O coupling of 2'-bromobiphenyl-2-carboxylic acid.
Keywords
- click chemistry, copper, heterogeneous catalysis, inductive heating, microreactors
ASJC Scopus subject areas
- Chemistry(all)
- Organic Chemistry
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In: Synlett, No. 13, 09.07.2010, p. 2009-2013.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Chemical synthesis with inductively heated copper flow reactors
AU - Ceylan, Sascha
AU - Klande, Tobias
AU - Vogt, Carla
AU - Friese, Carsten
AU - Kirschning, Andreas
PY - 2010/7/9
Y1 - 2010/7/9
N2 - Inductively heated copper wire inside a flow microreactor can serve as a source for a catalytic copper species that promotes 1,3-dipolar cycloadditions of alkynes with in situ formed azides to yield 1,2,3-triazoles. The same setup was used to carry out decarboxylations of 2-alkynoic acids and for the intramolecular C-O coupling of 2'-bromobiphenyl-2-carboxylic acid.
AB - Inductively heated copper wire inside a flow microreactor can serve as a source for a catalytic copper species that promotes 1,3-dipolar cycloadditions of alkynes with in situ formed azides to yield 1,2,3-triazoles. The same setup was used to carry out decarboxylations of 2-alkynoic acids and for the intramolecular C-O coupling of 2'-bromobiphenyl-2-carboxylic acid.
KW - click chemistry
KW - copper
KW - heterogeneous catalysis
KW - inductive heating
KW - microreactors
UR - http://www.scopus.com/inward/record.url?scp=77955372419&partnerID=8YFLogxK
U2 - 10.1055/s-0030-1258487
DO - 10.1055/s-0030-1258487
M3 - Article
AN - SCOPUS:77955372419
SP - 2009
EP - 2013
JO - Synlett
JF - Synlett
SN - 0936-5214
IS - 13
ER -