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Centre of Biomolecular Drug Research (BMWZ)

Organisational unit: Leibniz Research Centres

Type of address: Visitor address.
Schneiderberg 38
30167
Hannover
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Publications

  1. 2021
  2. Published

    Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics

    Gerckens, M., Schorpp, K., Pelizza, F., Wögrath, M., Reichau, K., Ma, H., Dworsky, A. M., Sengupta, A., Stoleriu, M. G., Heinzelmann, K., Merl-Pham, J., Irmler, M., Alsafadi, H. N., Trenkenschuh, E., Sarnova, L., Jirouskova, M., Frieß, W., Hauck, S. M., Beckers, J., Kneidinger, N., Behr, J., Hilgendorff, A., Hadian, K., Lindner, M., Königshoff, M., Eickelberg, O., Gregor, M., Plettenburg, O., Yildirim, A. Ö. & Burgstaller, G., 22 Dec 2021, In: Science advances. 7, 52, eabb3673.

    Research output: Contribution to journalArticleResearchpeer review

  3. Published

    Eukaryotic Box C/D methylation machinery has two non-symmetric protein assembly sites

    Höfler, S., Lukat, P., Blankenfeldt, W. & Carlomagno, T., Dec 2021, In: Scientific reports. 11, 17561.

    Research output: Contribution to journalArticleResearchpeer review

  4. Published

    Oxazaborolidinone-Mediated Asymmetric Bisvinylogous Mukaiyama Aldol Reaction

    Eggert, A., Etling, C., Millbrodt, L., Schulz, G. & Kalesse, M., 19 Nov 2021, In: Organic letters. 23, 22, p. 8722-8726 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  5. Published

    TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease

    O'Neill, T. J., Seeholzer, T., Gewies, A., Gehring, T., Giesert, F., Hamp, I., Graß, C., Schmidt, H., Kriegsmann, K., Tofaute, M. J., Demski, K., Poth, T., Rosenbaum, M., Schnalzger, T., Ruland, J., Göttlicher, M., Kriegsmann, M., Naumann, R., Heissmeyer, V., Plettenburg, O., Wurst, W. & Krappmann, D., 12 Nov 2021, In: Science Immunology. 6, 65, eabh2095.

    Research output: Contribution to journalArticleResearchpeer review

  6. Published

    Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens

    Pinkert, L., Lai, Y. H., Peukert, C., Hotop, S. K., Karge, B., Schulze, L. M., Grunenberg, J. & Brönstrup, M., 28 Oct 2021, In: Journal of medicinal chemistry. 64, 20, p. 15440–15460 21 p.

    Research output: Contribution to journalArticleResearchpeer review

  7. Published

    Identification of RNA Base Pairs and Complete Assignment of Nucleobase Resonances by Proton-Detected Solid-State NMR Spectroscopy at 100 kHz MAS

    Aguion, P. I., Kirkpatrick, J., Carlomagno, T. & Marchanka, A., 25 Oct 2021, In: Angewandte Chemie - International Edition. 60, 44, p. 23903-23910 8 p.

    Research output: Contribution to journalArticleResearchpeer review

  8. Published

    1H, 13C, and 15N backbone chemical-shift assignments of SARS-CoV-2 non-structural protein 1 (leader protein)

    Wang, Y., Kirkpatrick, J., zur Lage, S., Korn, S. M., Neißner, K., Schwalbe, H., Schlundt, A. & Carlomagno, T., Oct 2021, In: Biomolecular NMR assignments. 15, 2, p. 287-295 9 p.

    Research output: Contribution to journalArticleResearchpeer review

  9. Published

    Optimization of Artificial Siderophores as 68Ga-Complexed PET Tracers for in Vivo Imaging of Bacterial Infections

    Peukert, C., Langer, L. N. B., Wegener, S. M., Tutov, A., Bankstahl, J. P., Karge, B., Bengel, F. M., Ross, T. L. & Brönstrup, M., 26 Aug 2021, In: Journal of medicinal chemistry. 64, 16, p. 12359-12378 20 p.

    Research output: Contribution to journalArticleResearchpeer review

  10. Published

    Early Oxidative Transformations During the Biosynthesis of Terrein and Related Natural Products

    Kahlert, L., Bernardi, D., Hauser, M., Ióca, L. P., Berlinck, R. G. S., Skellam, E. J. & Cox, R. J., 16 Aug 2021, In: Chemistry – A European Journal. 27, 46, p. 11895-11903 9 p.

    Research output: Contribution to journalArticleResearchpeer review

  11. Published

    Structural and biochemical characterization of a dye-decolorizing peroxidase from dictyostelium discoideum

    Rai, A., Klare, J. P., Reinke, P. Y. A., Englmaier, F., Fohrer, J., Fedorov, R., Taft, M. H., Chizhov, I., Curth, U., Plettenburg, O. & Manstein, D. J., 10 Jun 2021, In: International Journal of Molecular Sciences. 22, 12, 6265.

    Research output: Contribution to journalArticleResearchpeer review

  12. Published

    Synthesis of Desepoxy-Tedanolide C

    Lücke, D. & Kalesse, M., 26 Apr 2021, In: Chemistry - a European journal. 27, 24, p. 7085-7089 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  13. Published

    In vitro studies of maleidride-forming enzymes

    Yin, S., Friedrich, S., Hrupins, V. & Cox, R. J., 21 Apr 2021, In: RSC Advances. 11, 25, p. 14922-14931 10 p.

    Research output: Contribution to journalArticleResearchpeer review

  14. Published

    High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain

    Höfler, S., Lukat, P., Blankenfeldt, W. & Carlomagno, T., Apr 2021, In: RNA. 27, 4, p. 496-512 17 p.

    Research output: Contribution to journalArticleResearchpeer review

  15. Published

    Drug Discovery in Academia

    Plettenburg, O., 22 Mar 2021, Successful Drug Discovery. Wiley-Blackwell, Vol. 5. p. 3-46 44 p.

    Research output: Chapter in book/report/conference proceedingContribution to book/anthologyResearchpeer review

  16. Published

    The Total Synthesis of Chondrochloren A

    Linne, Y., Bonandi, E., Tabet, C., Geldsetzer, J. & Kalesse, M., 22 Mar 2021, In: Angewandte Chemie . 60, 13, p. 6938-6942 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  17. Published

    Verfahren zum Bestimmen des physiologischen Belastungszustandes in einem Individuum und Vorrichtung hierfür

    Zeilinger, C., Reichel, T. M. & Krüger, K., 11 Mar 2021, IPC No. G01N33/50, G01N33/68, G01N33/53, Patent No. DE102019130890B3, 15 Nov 2019, Priority date 15 Nov 2019, Priority No. DE102019130890A

    Research output: Patent

  18. Published

    Verfahren und Vorrichtung zur Analyse sowie Arzneimittel zur Anwendung bei Schwerhörigkeit

    Zeilinger, C., Lenarz, T. & Warnecke, A., 18 Feb 2021, IPC No. A61K 31/7052 (2006.01) , 16 Aug 2019, Priority date 16 Aug 2019, Priority No. DE 102019212323

    Research output: Patent

  19. Published

    Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans

    Zhang, H., Hantke, V., Bruhnke, P., Skellam, E. J. & Cox, R. J., 10 Feb 2021, In: Chemistry - A European Journal. 27, 9, p. 3106-3113 8 p.

    Research output: Contribution to journalArticleResearchpeer review

  20. Published

    Total Synthesis and Structure Revision of Halioxepine

    Poock, C. & Kalesse, M., 21 Jan 2021, In: Chemistry - a European journal. 27, 5, p. 1615-1619 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  21. Published

    Hybridorubrins A-D: Azaphilone Heterodimers from Stromata of Hypoxylon fragiforme and Insights into the Biosynthetic Machinery for Azaphilone Diversification

    Becker, K., Pfütze, S., Kuhnert, E., Cox, R. J., Stadler, M. & Surup, F., 18 Jan 2021, In: Chemistry - A European Journal. 27, 4, p. 1438-1450 13 p.

    Research output: Contribution to journalArticleResearchpeer review

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