Publications
- 2021
- Published
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics
Gerckens, M., Schorpp, K., Pelizza, F., Wögrath, M., Reichau, K., Ma, H., Dworsky, A. M., Sengupta, A., Stoleriu, M. G., Heinzelmann, K., Merl-Pham, J., Irmler, M., Alsafadi, H. N., Trenkenschuh, E., Sarnova, L., Jirouskova, M., Frieß, W., Hauck, S. M., Beckers, J., Kneidinger, N., Behr, J., Hilgendorff, A., Hadian, K., Lindner, M., Königshoff, M., Eickelberg, O., Gregor, M., Plettenburg, O., Yildirim, A. Ö. & Burgstaller, G., 22 Dec 2021, In: Science advances. 7, 52, eabb3673.Research output: Contribution to journal › Article › Research › peer review
- Published
Eukaryotic Box C/D methylation machinery has two non-symmetric protein assembly sites
Höfler, S., Lukat, P., Blankenfeldt, W. & Carlomagno, T., Dec 2021, In: Scientific reports. 11, 17561.Research output: Contribution to journal › Article › Research › peer review
- Published
Oxazaborolidinone-Mediated Asymmetric Bisvinylogous Mukaiyama Aldol Reaction
Eggert, A., Etling, C., Millbrodt, L., Schulz, G. & Kalesse, M., 19 Nov 2021, In: Organic letters. 23, 22, p. 8722-8726 5 p.Research output: Contribution to journal › Article › Research › peer review
- Published
TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease
O'Neill, T. J., Seeholzer, T., Gewies, A., Gehring, T., Giesert, F., Hamp, I., Graß, C., Schmidt, H., Kriegsmann, K., Tofaute, M. J., Demski, K., Poth, T., Rosenbaum, M., Schnalzger, T., Ruland, J., Göttlicher, M., Kriegsmann, M., Naumann, R., Heissmeyer, V., Plettenburg, O., Wurst, W. & Krappmann, D., 12 Nov 2021, In: Science Immunology. 6, 65, eabh2095.Research output: Contribution to journal › Article › Research › peer review
- Published
Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens
Pinkert, L., Lai, Y. H., Peukert, C., Hotop, S. K., Karge, B., Schulze, L. M., Grunenberg, J. & Brönstrup, M., 28 Oct 2021, In: Journal of medicinal chemistry. 64, 20, p. 15440–15460 21 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Identification of RNA Base Pairs and Complete Assignment of Nucleobase Resonances by Proton-Detected Solid-State NMR Spectroscopy at 100 kHz MAS
Aguion, P. I., Kirkpatrick, J., Carlomagno, T. & Marchanka, A., 25 Oct 2021, In: Angewandte Chemie - International Edition. 60, 44, p. 23903-23910 8 p.Research output: Contribution to journal › Article › Research › peer review
- Published
1H, 13C, and 15N backbone chemical-shift assignments of SARS-CoV-2 non-structural protein 1 (leader protein)
Wang, Y., Kirkpatrick, J., zur Lage, S., Korn, S. M., Neißner, K., Schwalbe, H., Schlundt, A. & Carlomagno, T., Oct 2021, In: Biomolecular NMR assignments. 15, 2, p. 287-295 9 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Optimization of Artificial Siderophores as 68Ga-Complexed PET Tracers for in Vivo Imaging of Bacterial Infections
Peukert, C., Langer, L. N. B., Wegener, S. M., Tutov, A., Bankstahl, J. P., Karge, B., Bengel, F. M., Ross, T. L. & Brönstrup, M., 26 Aug 2021, In: Journal of medicinal chemistry. 64, 16, p. 12359-12378 20 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Early Oxidative Transformations During the Biosynthesis of Terrein and Related Natural Products
Kahlert, L., Bernardi, D., Hauser, M., Ióca, L. P., Berlinck, R. G. S., Skellam, E. J. & Cox, R. J., 16 Aug 2021, In: Chemistry – A European Journal. 27, 46, p. 11895-11903 9 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Structural and biochemical characterization of a dye-decolorizing peroxidase from dictyostelium discoideum
Rai, A., Klare, J. P., Reinke, P. Y. A., Englmaier, F., Fohrer, J., Fedorov, R., Taft, M. H., Chizhov, I., Curth, U., Plettenburg, O. & Manstein, D. J., 10 Jun 2021, In: International Journal of Molecular Sciences. 22, 12, 6265.Research output: Contribution to journal › Article › Research › peer review
- Published
Synthesis of Desepoxy-Tedanolide C
Lücke, D. & Kalesse, M., 26 Apr 2021, In: Chemistry - a European journal. 27, 24, p. 7085-7089 5 p.Research output: Contribution to journal › Article › Research › peer review
- Published
In vitro studies of maleidride-forming enzymes
Yin, S., Friedrich, S., Hrupins, V. & Cox, R. J., 21 Apr 2021, In: RSC Advances. 11, 25, p. 14922-14931 10 p.Research output: Contribution to journal › Article › Research › peer review
- Published
High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain
Höfler, S., Lukat, P., Blankenfeldt, W. & Carlomagno, T., Apr 2021, In: RNA. 27, 4, p. 496-512 17 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Drug Discovery in Academia
Plettenburg, O., 22 Mar 2021, Successful Drug Discovery. Wiley-Blackwell, Vol. 5. p. 3-46 44 p.Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
- Published
The Total Synthesis of Chondrochloren A
Linne, Y., Bonandi, E., Tabet, C., Geldsetzer, J. & Kalesse, M., 22 Mar 2021, In: Angewandte Chemie . 60, 13, p. 6938-6942 5 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Verfahren zum Bestimmen des physiologischen Belastungszustandes in einem Individuum und Vorrichtung hierfür
Zeilinger, C., Reichel, T. M. & Krüger, K., 11 Mar 2021, IPC No. G01N33/50, G01N33/68, G01N33/53, Patent No. DE102019130890B3, 15 Nov 2019, Priority date 15 Nov 2019, Priority No. DE102019130890AResearch output: Patent
- Published
Verfahren und Vorrichtung zur Analyse sowie Arzneimittel zur Anwendung bei Schwerhörigkeit
Zeilinger, C., Lenarz, T. & Warnecke, A., 18 Feb 2021, IPC No. A61K 31/7052 (2006.01) , 16 Aug 2019, Priority date 16 Aug 2019, Priority No. DE 102019212323Research output: Patent
- Published
Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans
Zhang, H., Hantke, V., Bruhnke, P., Skellam, E. J. & Cox, R. J., 10 Feb 2021, In: Chemistry - A European Journal. 27, 9, p. 3106-3113 8 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Total Synthesis and Structure Revision of Halioxepine
Poock, C. & Kalesse, M., 21 Jan 2021, In: Chemistry - a European journal. 27, 5, p. 1615-1619 5 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Hybridorubrins A-D: Azaphilone Heterodimers from Stromata of Hypoxylon fragiforme and Insights into the Biosynthetic Machinery for Azaphilone Diversification
Becker, K., Pfütze, S., Kuhnert, E., Cox, R. J., Stadler, M. & Surup, F., 18 Jan 2021, In: Chemistry - A European Journal. 27, 4, p. 1438-1450 13 p.Research output: Contribution to journal › Article › Research › peer review