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Centre of Biomolecular Drug Research (BMWZ)

Organisational unit: Leibniz Research Centres

Type of address: Visitor address.
Schneiderberg 38
30167
Hannover
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1 - 20 out of 307Page size: 20

Publications

  1. 2026
  2. Published

    Exploring the Substitution of the C21-OAc Moiety in [11]Cytochalasans: Synthesis and Evaluation of Fluorophore Conjugates

    Kagho, M. D., Schmidt, K., Chakrabarti, A., Karger, M., Lambert, C., Hauser, M., Cox, R. J., Rottner, K., Stadler, M., Stradal, T. E. & Klahn, P., 8 Jan 2026, In: CHEMBIOCHEM. 27, 1, e202500794.

    Research output: Contribution to journal › Article › Research › peer review

  3. 2025
  4. Published

    Quantum mechanics-driven structure-activity relationship study of PEX5-PEX14 protein-protein interaction inhibitors based on a dibenzo[b,e]azepin-6(6H)-one scaffold

    Nowacki, M., Menezes, F., Pykacz, E., Popiołek, M., Napolitano, V., Krishna, C. K., Kalel, V. C., Erdmann, R., Fröhlich, T., Plettenburg, O., Sattler, M., Popowicz, G. M. & Dawidowski, M., 15 Nov 2025, In: European Journal of Medicinal Chemistry. 298, 117979.

    Research output: Contribution to journal › Article › Research › peer review

  5. Published

    Discovery of corynanthe synthases in Camptotheca acuminata: medium-chain dehydrogenase/reductase-based gateway to corynanthe-type compound diversification

    Bui, V. H., Nguyen, T. A. M., Kim, T., Liu, S., Seligmann, B., Daneshgar, P., Nguyen, T. D., Zandberg, W. F., Franke, J. & Dang, T. T. T., 13 Aug 2025, In: PLANTA. 262, 4, 80.

    Research output: Contribution to journal › Article › Research › peer review

  6. Published

    Synthesis of l-β-(6-azulenyl)alanine and the fluorescent actin disruptor (6-azuleno)chalasin H

    Hauser, M., Schmidt, K., Beiderwieden, L., Yi, C., Gerdes, K., Kalesse, M., Gerke, J., Stradal, T. E. & Cox, R. J., 22 Jul 2025, In: RSC Advances. 15, 32, p. 26048-26051 4 p.

    Research output: Contribution to journal › Article › Research › peer review

  7. Published

    Facile High-Throughput Pre-purification of Biological Samples for Library-Scale Peptide Interaction Studies

    Beutling, U., Hotop, S. K., Frank, R. & Brönstrup, M., 16 Jul 2025, Methods in Molecular Biology. p. 181-187 7 p. (Methods in Molecular Biology; vol. 2934).

    Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review

  8. Published

    Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis

    Hakim, S. E., Choudhary, N., Malhotra, K., Peng, J., Bültemeier, A., Arafa, A., Friedhoff, R., Bauer, M., Eikenberg, J., Witte, C. P., Herde, M., Heretsch, P., Pucker, B. & Franke, J., 10 Jul 2025, In: Nature Communications. 16, 1, 6367.

    Research output: Contribution to journal › Article › Research › peer review

  9. Published

    Development of a microarray based telomerase binding assay reveals unusual binding of a cytochalasin derivative

    Ye, J. L., Fan, L., Bär, C., Thum, T., Plettenburg, O., Cox, R. J. & Zeilinger, C., 4 Jun 2025, In: Scientific reports. 15, 1, 19515.

    Research output: Contribution to journal › Article › Research › peer review

  10. Published

    NMR chemical shift assignment of the IMLV methyl groups of a di-domain of the Tomaymycin non-ribosomal peptide synthetase

    Kirkpatrick, J. P., Karanth, M. N. & Carlomagno, T., Jun 2025, In: Biomolecular NMR assignments. 19, 1, p. 153-164 12 p.

    Research output: Contribution to journal › Article › Research › peer review

  11. Published

    Lienhwalides: Unique Tropolone–Maleidride Hybrids from Hypoxylon lienhwacheense

    Schmidt, K., Charria-Girón, E., Gorelik, T. E., Kleeberg, C., Muema, J. M., Heitkämper, S., Verwaaijen, B., Kuhnert, E., Gerke, J., Kalinowski, J., Hyde, K. D., Stadler, M., Cox, R. & Surup, F., 28 May 2025, In: CHEMBIOCHEM. 26, 10, e202500037.

    Research output: Contribution to journal › Article › Research › peer review

  12. Published

    Discovery of synthetic small molecules targeting the central regulator of Salmonella pathogenicity

    Boudrioua, A., Joiner, J. D., Grin, I., Kronenberger, T., Korotkov, V. S., Steinchen, W., Kohler, A., Schminke, S., Schulte, J. C., Pietsch, M., Naini, A., Kalverkamp, S., Hotop, S. K., Coyle, T., Piselli, C., Coles, M., Rox, K., Marschal, M., Bange, G., Flieger, A., Poso, A., Brönstrup, M., Hartmann, M. D. & Wagner, S., 11 Apr 2025, In: Science advances. 11, 15, 23 p., eadr5235.

    Research output: Contribution to journal › Article › Research › peer review

  13. Published

    Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections

    Shekhar, A., Di Lucrezia, R., Jerye, K., Korotkov, V. S., Harmrolfs, K., Rox, K., Weich, H. A., Ghai, I., Delhommel, F., Becher, I., Degenhart, C., Fansa, E., Unger, A., Habenberger, P., Klebl, B., Lukat, P., Schmelz, S., Henke, S., Borgert, S., Lang, J. C., Sasse, F., Diestel, R., Richter, C., Schneider-Daum, N., Hinkelmann, B., Niemz, J., Lehr, C. M., Jänsch, L., Huehn, J., Alm, R., Savitski, M., Welte, T., Hesterkamp, T., Sattler, M., Winterhalter, M., Blankenfeldt, W., Medina, E., Bilitewski, U., Dinkel, K. & Brönstrup, M., 9 Apr 2025, In: Cell Host and Microbe. 33, 4, p. 560-572.e21

    Research output: Contribution to journal › Article › Research › peer review

  14. Published

    Expansion of the Stereochemical Space of Triterpenes by Mining Noncanonical Oxidosqualene Cyclases Across the Diversity of Green Plants

    Hakim, S. E., Liu, S., Herzog, R., Arafa, A., de Vries, J., Dräger, G. & Franke, J., 26 Mar 2025, In: Journal of the American Chemical Society. 147, 12, p. 10320-10330 11 p.

    Research output: Contribution to journal › Article › Research › peer review

  15. Published

    Stress biomarker test for athletes with portable optical detector and functionalized quantum dots

    Kishore, A., Varughese, A. M., Roth, B. & Zeilinger, C., 20 Mar 2025, Biophotonics in Exercise Science, Sports Medicine, Health Monitoring Technologies, and Wearables VI. Shadgan, B. & Gandjbakhche, A. H. (eds.). SPIE, 13 p. 133130A. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 13313).

    Research output: Chapter in book/report/conference proceeding › Conference contribution › Research › peer review

  16. Published

    Synthese neuartiger Farbstoffe zur in vivo-Bildgebung

    Unger, E., 13 Mar 2025, Hannover. 545 p.

    Research output: Thesis › Doctoral thesis

  17. Published

    Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus

    Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M. & Kirschning, A., 12 Mar 2025, In: Nature Communications. 16, 1, 13 p., 2464.

    Research output: Contribution to journal › Article › Research › peer review

  18. Published

    Antibacterials with Novel Chemical Scaffolds in Clinical Development

    Heimann, D., Kohnhäuser, D., Kohnhäuser, A. J. & Brönstrup, M., Mar 2025, In: DRUGS. 85, p. 293–323 31 p., 115484.

    Research output: Contribution to journal › Article › Research › peer review

  19. Published

    Structure-Based Optimization of Pyridone α-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease

    Akula, R. K., El Kilani, H., Metzen, A., Röske, J., Zhang, K., Göhl, M., Arisetti, N., Marsh, G. P., Maple, H. J., Cooper, M. S., Karadogan, B., Jochmans, D., Neyts, J., Rox, K., Hilgenfeld, R. & Brönstrup, M., 13 Feb 2025, In: Journal of medicinal chemistry. 68, 3, p. 2920–2941 22 p.

    Research output: Contribution to journal › Article › Research › peer review

  20. Published

    An updated patent review of MALT1 inhibitors (2021–present)

    Brvar, M., O’Neill, T. J., Plettenburg, O. & Krappmann, D., 2025, In: Expert Opinion on Therapeutic Patents. 35, 6, p. 639-656 18 p.

    Research output: Contribution to journal › Review article › Research › peer review

  21. 2024
  22. Published

    Cytotoxic and proliferation-inhibitory activity of natural and synthetic fungal tropolone sesquiterpenoids in various cell lines

    Bergmann, T. C., Menssen, M., Schotte, C., Cox, R. J. & Lee-Thedieck, C., 30 Nov 2024, In: Heliyon. 10, 22, e37713.

    Research output: Contribution to journal › Article › Research › peer review

  23. Published

    Inceptor binds to and directs insulin towards lysosomal degradation in β cells

    Siehler, J., Bilekova, S., Chapouton, P., Dema, A., Albanese, P., Tamara, S., Jain, C., Sterr, M., Enos, S. J., Chen, C., Malhotra, C., Villalba, A., Schomann, L., Bhattacharya, S., Feng, J., Akgün Canan, M., Ribaudo, F., Ansarullah, Burtscher, I., Ahlbrecht, C., Plettenburg, O., Kurth, T., Scharfmann, R., Speier, S., Scheltema, R. A. & Lickert, H., 25 Nov 2024, In: Nature Metabolism. 6, 12, p. 2374-2390 17 p., e202206132.

    Research output: Contribution to journal › Article › Research › peer review

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