Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 1269-1271 |
| Seitenumfang | 3 |
| Fachzeitschrift | Tetrahedron letters |
| Jahrgang | 42 |
| Ausgabenummer | 7 |
| Publikationsstatus | Veröffentlicht - 12 Feb. 2001 |
Abstract
The first vinylogous Mukaiyama aldol reactions with tris(pentafluorophenyl)borane and triphenylborane are described. Both Lewis acids diastereoselectively generate the C19-C21 all-syn stereo triad of ratjadone, and in the case of tris(pentafluorophenyl)borane the reaction proceeds with substoichiometric amounts.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Pharmakologie, Toxikologie und Pharmazie (insg.)
- Wirkstoffforschung
- Chemie (insg.)
- Organische Chemie
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in: Tetrahedron letters, Jahrgang 42, Nr. 7, 12.02.2001, S. 1269-1271.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Vinylogous Mukaiyama aldol reactions with triarylboranes
AU - Christmann, Mathias
AU - Kalesse, Markus
N1 - Funding Information: This work was supported by the Deutsche Forschungsgemeinschaft, the Volkswagenstiftung (Meeresbiotechnologie) and the Fonds der Chemischen Industrie.
PY - 2001/2/12
Y1 - 2001/2/12
N2 - The first vinylogous Mukaiyama aldol reactions with tris(pentafluorophenyl)borane and triphenylborane are described. Both Lewis acids diastereoselectively generate the C19-C21 all-syn stereo triad of ratjadone, and in the case of tris(pentafluorophenyl)borane the reaction proceeds with substoichiometric amounts.
AB - The first vinylogous Mukaiyama aldol reactions with tris(pentafluorophenyl)borane and triphenylborane are described. Both Lewis acids diastereoselectively generate the C19-C21 all-syn stereo triad of ratjadone, and in the case of tris(pentafluorophenyl)borane the reaction proceeds with substoichiometric amounts.
KW - Polyketide synthesis
KW - Ratjadone
KW - Vinylogous Mukaiyama aldol reaction
UR - http://www.scopus.com/inward/record.url?scp=0035847523&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(00)02254-1
DO - 10.1016/S0040-4039(00)02254-1
M3 - Article
AN - SCOPUS:0035847523
VL - 42
SP - 1269
EP - 1271
JO - Tetrahedron letters
JF - Tetrahedron letters
SN - 0040-4039
IS - 7
ER -