Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 3485-3488 |
| Seitenumfang | 4 |
| Fachzeitschrift | Organic letters |
| Jahrgang | 8 |
| Ausgabenummer | 16 |
| Publikationsstatus | Veröffentlicht - 3 Aug. 2006 |
Abstract
The tandem intramolecular Michael-aldol reaction was studied as a tool for the construction of the C-ring of hexacyclinic acid. By changing the reaction conditions it was possible to selectively obtain either the kinetic or the thermodynamic product. Retro-aldol reaction and subsequent epimerization provides four individual cyclopentane derivatives that can be incorporated as building blocks in natural product syntheses.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Chemie (insg.)
- Physikalische und Theoretische Chemie
- Chemie (insg.)
- Organische Chemie
Zitieren
- Standard
- Harvard
- Apa
- Vancouver
- BibTex
- RIS
in: Organic letters, Jahrgang 8, Nr. 16, 03.08.2006, S. 3485-3488.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Tandem intramolecular Michael-Aldol reaction as a tool for the construction of the C-ring of hexacyclinic acid
AU - Stelmakh, Andriy
AU - Stellfeld, Timo
AU - Kalesse, Markus
PY - 2006/8/3
Y1 - 2006/8/3
N2 - The tandem intramolecular Michael-aldol reaction was studied as a tool for the construction of the C-ring of hexacyclinic acid. By changing the reaction conditions it was possible to selectively obtain either the kinetic or the thermodynamic product. Retro-aldol reaction and subsequent epimerization provides four individual cyclopentane derivatives that can be incorporated as building blocks in natural product syntheses.
AB - The tandem intramolecular Michael-aldol reaction was studied as a tool for the construction of the C-ring of hexacyclinic acid. By changing the reaction conditions it was possible to selectively obtain either the kinetic or the thermodynamic product. Retro-aldol reaction and subsequent epimerization provides four individual cyclopentane derivatives that can be incorporated as building blocks in natural product syntheses.
UR - http://www.scopus.com/inward/record.url?scp=33747243871&partnerID=8YFLogxK
U2 - 10.1021/ol061096q
DO - 10.1021/ol061096q
M3 - Article
C2 - 16869641
AN - SCOPUS:33747243871
VL - 8
SP - 3485
EP - 3488
JO - Organic letters
JF - Organic letters
SN - 1523-7060
IS - 16
ER -