Rotary swaged biocompatible Zn-1Mg-0.1Mn alloy with improved strength and ductility

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autorschaft

  • N. Martynenko
  • N. Anisimova
  • N. Tabachkova
  • M. Zheleznyi
  • D. Prosvirnin
  • M. Shinkareva
  • G. Rybalchenko
  • O. Rybalchenko
  • E. Lukyanova
  • D. Temralieva
  • N. Pashintseva
  • G. Babayeva
  • A. Koltygin
  • V. Andreev
  • M. Kiselevskiy
  • S. Dobatkin
  • B. Straumal
  • G. Gerstein

Organisationseinheiten

Externe Organisationen

  • Russian Academy of Sciences (RAS)
  • Russian Academy of Medical Sciences - N.N. Blokhin Russian Cancer Research Center
  • National University of Science and Technology MISIS
  • RAS - General Physics Institute
  • Lebedev Physical Institute of the Russian Academy of Sciences (LPI RAS)
  • Peoples' Friendship University of Russia (RUDN)
  • RAS - Institute of Solid State Physics
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Aufsatznummer180995
Seitenumfang11
FachzeitschriftJournal of alloys and compounds
Jahrgang1031
Frühes Online-Datum15 Mai 2025
PublikationsstatusVeröffentlicht - 5 Juni 2025

Abstract

The effect of rotary swaging (RS) on the microstructure, mechanical properties, corrosion resistance and biocompatibility in vitro and in vivo of the Zn-1Mg-0.1Mn (wt%) alloy was studied in this work. A structure with α-Zn grains elongated along the deformation direction and spherical particles of the eutectic phase are formed in the Zn-1Mg-0.1Mn alloy after RS. RS also leads to the formation of an ultrafine-grained structure with a grain size of less than 1 μm and the precipitation of MnZn13 particles. The formation of such a microstructure increases the strength (YS up to 274 ± 8 MPa, UTS up to 295 ± 4 MPa) and fatigue limit (σR = 130 MPa) of the alloy without loss of ductility. At the same time, RS does not lead to deterioration of the corrosion resistance of the alloy and cause a tendency to slow down the degradation process. The biocompatibility in vitro of the Zn-1Mg-0.1Mn alloy both before and after RS is at an acceptable for medical use level. It is also interesting that the alloy does not promote the growth of adenocarcinoma cells line SKBR3. Implantation of the alloy under the periosteum of the mice tibia does not cause the formation of foci of osteomalacia or accumulation of pus, as well as processes of rejection of samples or tissue inflammation. In this regard, it can be concluded that the alloy can be considered a promising material for use in orthopedic oncology.

ASJC Scopus Sachgebiete

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Rotary swaged biocompatible Zn-1Mg-0.1Mn alloy with improved strength and ductility. / Martynenko, N.; Anisimova, N.; Tabachkova, N. et al.
in: Journal of alloys and compounds, Jahrgang 1031, 180995, 05.06.2025.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Martynenko, N, Anisimova, N, Tabachkova, N, Zheleznyi, M, Prosvirnin, D, Shinkareva, M, Rybalchenko, G, Rybalchenko, O, Lukyanova, E, Temralieva, D, Pashintseva, N, Babayeva, G, Koltygin, A, Andreev, V, Kiselevskiy, M, Dobatkin, S, Straumal, B & Gerstein, G 2025, 'Rotary swaged biocompatible Zn-1Mg-0.1Mn alloy with improved strength and ductility', Journal of alloys and compounds, Jg. 1031, 180995. https://doi.org/10.1016/j.jallcom.2025.180995
Martynenko, N., Anisimova, N., Tabachkova, N., Zheleznyi, M., Prosvirnin, D., Shinkareva, M., Rybalchenko, G., Rybalchenko, O., Lukyanova, E., Temralieva, D., Pashintseva, N., Babayeva, G., Koltygin, A., Andreev, V., Kiselevskiy, M., Dobatkin, S., Straumal, B., & Gerstein, G. (2025). Rotary swaged biocompatible Zn-1Mg-0.1Mn alloy with improved strength and ductility. Journal of alloys and compounds, 1031, Artikel 180995. https://doi.org/10.1016/j.jallcom.2025.180995
Martynenko N, Anisimova N, Tabachkova N, Zheleznyi M, Prosvirnin D, Shinkareva M et al. Rotary swaged biocompatible Zn-1Mg-0.1Mn alloy with improved strength and ductility. Journal of alloys and compounds. 2025 Jun 5;1031:180995. Epub 2025 Mai 15. doi: 10.1016/j.jallcom.2025.180995
Martynenko, N. ; Anisimova, N. ; Tabachkova, N. et al. / Rotary swaged biocompatible Zn-1Mg-0.1Mn alloy with improved strength and ductility. in: Journal of alloys and compounds. 2025 ; Jahrgang 1031.
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title = "Rotary swaged biocompatible Zn-1Mg-0.1Mn alloy with improved strength and ductility",
abstract = "The effect of rotary swaging (RS) on the microstructure, mechanical properties, corrosion resistance and biocompatibility in vitro and in vivo of the Zn-1Mg-0.1Mn (wt%) alloy was studied in this work. A structure with α-Zn grains elongated along the deformation direction and spherical particles of the eutectic phase are formed in the Zn-1Mg-0.1Mn alloy after RS. RS also leads to the formation of an ultrafine-grained structure with a grain size of less than 1 μm and the precipitation of MnZn13 particles. The formation of such a microstructure increases the strength (YS up to 274 ± 8 MPa, UTS up to 295 ± 4 MPa) and fatigue limit (σR = 130 MPa) of the alloy without loss of ductility. At the same time, RS does not lead to deterioration of the corrosion resistance of the alloy and cause a tendency to slow down the degradation process. The biocompatibility in vitro of the Zn-1Mg-0.1Mn alloy both before and after RS is at an acceptable for medical use level. It is also interesting that the alloy does not promote the growth of adenocarcinoma cells line SKBR3. Implantation of the alloy under the periosteum of the mice tibia does not cause the formation of foci of osteomalacia or accumulation of pus, as well as processes of rejection of samples or tissue inflammation. In this regard, it can be concluded that the alloy can be considered a promising material for use in orthopedic oncology.",
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TY - JOUR

T1 - Rotary swaged biocompatible Zn-1Mg-0.1Mn alloy with improved strength and ductility

AU - Martynenko, N.

AU - Anisimova, N.

AU - Tabachkova, N.

AU - Zheleznyi, M.

AU - Prosvirnin, D.

AU - Shinkareva, M.

AU - Rybalchenko, G.

AU - Rybalchenko, O.

AU - Lukyanova, E.

AU - Temralieva, D.

AU - Pashintseva, N.

AU - Babayeva, G.

AU - Koltygin, A.

AU - Andreev, V.

AU - Kiselevskiy, M.

AU - Dobatkin, S.

AU - Straumal, B.

AU - Gerstein, G.

N1 - Publisher Copyright: © 2025 Elsevier B.V.

PY - 2025/6/5

Y1 - 2025/6/5

N2 - The effect of rotary swaging (RS) on the microstructure, mechanical properties, corrosion resistance and biocompatibility in vitro and in vivo of the Zn-1Mg-0.1Mn (wt%) alloy was studied in this work. A structure with α-Zn grains elongated along the deformation direction and spherical particles of the eutectic phase are formed in the Zn-1Mg-0.1Mn alloy after RS. RS also leads to the formation of an ultrafine-grained structure with a grain size of less than 1 μm and the precipitation of MnZn13 particles. The formation of such a microstructure increases the strength (YS up to 274 ± 8 MPa, UTS up to 295 ± 4 MPa) and fatigue limit (σR = 130 MPa) of the alloy without loss of ductility. At the same time, RS does not lead to deterioration of the corrosion resistance of the alloy and cause a tendency to slow down the degradation process. The biocompatibility in vitro of the Zn-1Mg-0.1Mn alloy both before and after RS is at an acceptable for medical use level. It is also interesting that the alloy does not promote the growth of adenocarcinoma cells line SKBR3. Implantation of the alloy under the periosteum of the mice tibia does not cause the formation of foci of osteomalacia or accumulation of pus, as well as processes of rejection of samples or tissue inflammation. In this regard, it can be concluded that the alloy can be considered a promising material for use in orthopedic oncology.

AB - The effect of rotary swaging (RS) on the microstructure, mechanical properties, corrosion resistance and biocompatibility in vitro and in vivo of the Zn-1Mg-0.1Mn (wt%) alloy was studied in this work. A structure with α-Zn grains elongated along the deformation direction and spherical particles of the eutectic phase are formed in the Zn-1Mg-0.1Mn alloy after RS. RS also leads to the formation of an ultrafine-grained structure with a grain size of less than 1 μm and the precipitation of MnZn13 particles. The formation of such a microstructure increases the strength (YS up to 274 ± 8 MPa, UTS up to 295 ± 4 MPa) and fatigue limit (σR = 130 MPa) of the alloy without loss of ductility. At the same time, RS does not lead to deterioration of the corrosion resistance of the alloy and cause a tendency to slow down the degradation process. The biocompatibility in vitro of the Zn-1Mg-0.1Mn alloy both before and after RS is at an acceptable for medical use level. It is also interesting that the alloy does not promote the growth of adenocarcinoma cells line SKBR3. Implantation of the alloy under the periosteum of the mice tibia does not cause the formation of foci of osteomalacia or accumulation of pus, as well as processes of rejection of samples or tissue inflammation. In this regard, it can be concluded that the alloy can be considered a promising material for use in orthopedic oncology.

KW - Biocompatibility in vitro

KW - Corrosion behavior

KW - Fatigue life

KW - Mechanical properties

KW - Osteointegration

KW - Rotary swaging

KW - Zinc alloy

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DO - 10.1016/j.jallcom.2025.180995

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VL - 1031

JO - Journal of alloys and compounds

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