Process intensification in oxidative biocatalysis

Publikation: Beitrag in FachzeitschriftÜbersichtsarbeitForschungPeer-Review

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OriginalspracheEnglisch
Aufsatznummer100692
FachzeitschriftCurrent Opinion in Green and Sustainable Chemistry
Jahrgang38
Frühes Online-Datum31 Aug. 2022
PublikationsstatusVeröffentlicht - Dez. 2022

Abstract

In the last ten years, the number of publications related to process intensification (PI) has been quadrupled. This increasing interest that created many innovations can be found not only in chemo-catalytic processes but has also reached the field of enzymatic processes. The recent scientific and technological advances in bioprocess intensification have been dedicated to improving the use of enzymes in selective oxidative reactions, obtaining more environmentally friendly and resource efficient applications. In this mini-review, we provide an overview of the different PI definitions, and recent studies focusing on intensification of oxidative biocatalytic reactions regarding (i) non-conventional media, (ii) process data and analytics, (iii) reactor engineering, and (iv) downstream processing. Remarking how the advances of other fields can be used for process intensification and for obtaining new goals (e.g., PI 4.0). Model-based simulations and new sensor technologies can guarantee optimal and more automated processes with new reactor designs, together with the use of non-conventional media and enzyme immobilization, to intensify biocatalytic oxidation processes.

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Process intensification in oxidative biocatalysis. / Vernet, Guillem; Hobisch, Markus; Kara, Selin.
in: Current Opinion in Green and Sustainable Chemistry, Jahrgang 38, 100692, 12.2022.

Publikation: Beitrag in FachzeitschriftÜbersichtsarbeitForschungPeer-Review

Vernet, G, Hobisch, M & Kara, S 2022, 'Process intensification in oxidative biocatalysis', Current Opinion in Green and Sustainable Chemistry, Jg. 38, 100692. https://doi.org/10.1016/j.cogsc.2022.100692
Vernet, G., Hobisch, M., & Kara, S. (2022). Process intensification in oxidative biocatalysis. Current Opinion in Green and Sustainable Chemistry, 38, Artikel 100692. https://doi.org/10.1016/j.cogsc.2022.100692
Vernet G, Hobisch M, Kara S. Process intensification in oxidative biocatalysis. Current Opinion in Green and Sustainable Chemistry. 2022 Dez;38:100692. Epub 2022 Aug 31. doi: 10.1016/j.cogsc.2022.100692
Vernet, Guillem ; Hobisch, Markus ; Kara, Selin. / Process intensification in oxidative biocatalysis. in: Current Opinion in Green and Sustainable Chemistry. 2022 ; Jahrgang 38.
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AU - Vernet, Guillem

AU - Hobisch, Markus

AU - Kara, Selin

N1 - Funding Information: Aarhus University Research Foundation (AUFF, Aarhus Universitets Forskningsfond) is acknowledged for the financial support.

PY - 2022/12

Y1 - 2022/12

N2 - In the last ten years, the number of publications related to process intensification (PI) has been quadrupled. This increasing interest that created many innovations can be found not only in chemo-catalytic processes but has also reached the field of enzymatic processes. The recent scientific and technological advances in bioprocess intensification have been dedicated to improving the use of enzymes in selective oxidative reactions, obtaining more environmentally friendly and resource efficient applications. In this mini-review, we provide an overview of the different PI definitions, and recent studies focusing on intensification of oxidative biocatalytic reactions regarding (i) non-conventional media, (ii) process data and analytics, (iii) reactor engineering, and (iv) downstream processing. Remarking how the advances of other fields can be used for process intensification and for obtaining new goals (e.g., PI 4.0). Model-based simulations and new sensor technologies can guarantee optimal and more automated processes with new reactor designs, together with the use of non-conventional media and enzyme immobilization, to intensify biocatalytic oxidation processes.

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KW - Biocatalysis

KW - Downstream processing

KW - Non-conventional media

KW - Oxidative enzymes

KW - Process data

KW - Reactor engineering

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