Details
| Originalsprache | Englisch |
|---|---|
| Seiten | 325 |
| Seitenumfang | 1 |
| Publikationsstatus | Veröffentlicht - 1996 |
| Veranstaltung | 1996 Conference on Lasers and Electro-Optics Europe, CLEO/Europe - Hamburg, Deutschland Dauer: 8 Sept. 1996 → 13 Sept. 1996 |
Konferenz
| Konferenz | 1996 Conference on Lasers and Electro-Optics Europe, CLEO/Europe |
|---|---|
| Land/Gebiet | Deutschland |
| Ort | Hamburg |
| Zeitraum | 8 Sept. 1996 → 13 Sept. 1996 |
Abstract
These studies are directed towards an on-line monitoring of tissue properties during medical laser applications for diagnostics and therapy. These properties are in particular the optical parameters (i.e.absorption and scattering) and in the case of invasive treatments such as photoablation the depth of the incision. The determination of these properties can be performed by an interpretation of pressure signals which arise in the tissue during irradiation with pulsed laser light [1, 2]. For this purpose the fluence of the applied laser pulses was kept in the thermoelastic regime. At these fluences, the temperature of the irradiated region is increased by not more than a few Kelvin. For the detection of the laser induced acoustic transients piezoelectric transducers were used. The generated pressure signals are influenced by numerous processes during generation, propagation and detection. To study each process in particular, specific experiments were performed using biological tissue in vitro and model substances such as polymethylmethacrylate (PMMA), gelatine and silicon. The optical properties of these substances were varied by adding different concentrations of dye-solutions. Especially acoustical diffraction causes a strong distortion of the shape and spatial oscillations in the amplitude of the transients [3, 4]. These phenomenons were investigated experimentally and verified theoretically.
ASJC Scopus Sachgebiete
- Ingenieurwesen (insg.)
- Steuerungs- und Systemtechnik
- Ingenieurwesen (insg.)
- Elektrotechnik und Elektronik
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1996. 325 Beitrag in 1996 Conference on Lasers and Electro-Optics Europe, CLEO/Europe, Hamburg, Deutschland.
Publikation: Konferenzbeitrag › Paper › Forschung › Peer-Review
}
TY - CONF
T1 - Photoacoustic determination of optical parameters of biological tissue
AU - Ruff, Chr
AU - Lohmann, S.
AU - Lubatschowski, H.
AU - Ertmer, W.
PY - 1996
Y1 - 1996
N2 - These studies are directed towards an on-line monitoring of tissue properties during medical laser applications for diagnostics and therapy. These properties are in particular the optical parameters (i.e.absorption and scattering) and in the case of invasive treatments such as photoablation the depth of the incision. The determination of these properties can be performed by an interpretation of pressure signals which arise in the tissue during irradiation with pulsed laser light [1, 2]. For this purpose the fluence of the applied laser pulses was kept in the thermoelastic regime. At these fluences, the temperature of the irradiated region is increased by not more than a few Kelvin. For the detection of the laser induced acoustic transients piezoelectric transducers were used. The generated pressure signals are influenced by numerous processes during generation, propagation and detection. To study each process in particular, specific experiments were performed using biological tissue in vitro and model substances such as polymethylmethacrylate (PMMA), gelatine and silicon. The optical properties of these substances were varied by adding different concentrations of dye-solutions. Especially acoustical diffraction causes a strong distortion of the shape and spatial oscillations in the amplitude of the transients [3, 4]. These phenomenons were investigated experimentally and verified theoretically.
AB - These studies are directed towards an on-line monitoring of tissue properties during medical laser applications for diagnostics and therapy. These properties are in particular the optical parameters (i.e.absorption and scattering) and in the case of invasive treatments such as photoablation the depth of the incision. The determination of these properties can be performed by an interpretation of pressure signals which arise in the tissue during irradiation with pulsed laser light [1, 2]. For this purpose the fluence of the applied laser pulses was kept in the thermoelastic regime. At these fluences, the temperature of the irradiated region is increased by not more than a few Kelvin. For the detection of the laser induced acoustic transients piezoelectric transducers were used. The generated pressure signals are influenced by numerous processes during generation, propagation and detection. To study each process in particular, specific experiments were performed using biological tissue in vitro and model substances such as polymethylmethacrylate (PMMA), gelatine and silicon. The optical properties of these substances were varied by adding different concentrations of dye-solutions. Especially acoustical diffraction causes a strong distortion of the shape and spatial oscillations in the amplitude of the transients [3, 4]. These phenomenons were investigated experimentally and verified theoretically.
UR - http://www.scopus.com/inward/record.url?scp=0029766301&partnerID=8YFLogxK
M3 - Paper
AN - SCOPUS:0029766301
SP - 325
T2 - 1996 Conference on Lasers and Electro-Optics Europe, CLEO/Europe
Y2 - 8 September 1996 through 13 September 1996
ER -