Optoakustische Gewebsdifferenzierung zur Optimierung von Laserzyklophotokoagulation: Transsklerale Detektion laserinduzierter optoakustischer Drucktransienten

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autorschaft

  • I. A. Bruder
  • A. Büsching
  • U. Oberheide
  • H. Lubatschowski
  • H. Welling
  • W. Ertmer

Organisationseinheiten

Externe Organisationen

  • Laser Zentrum Hannover e.V. (LZH)
Forschungs-netzwerk anzeigen

Details

Titel in ÜbersetzungOptoacoustical tissue alteration for optimizing laser cyclophototoagulation.: Transscleral detection of laser-induced optoacoustical pressure transients
OriginalspracheDeutsch
Seiten (von - bis)258-264
Seitenumfang7
FachzeitschriftOPHTHALMOLOGE
Jahrgang98
Ausgabenummer3
PublikationsstatusVeröffentlicht - März 2001

Abstract

Background. Considerable problems occur in transscleral laser cyclophotocoagulation concerning energy dosage. We investigated the feasibility of localizing the ciliary body by the detection of thermoelastic pressure transients and of supervising on-line the degree of tissue damage during treatment. Method. We used a specially designed handpiece to apply short pulsed laser radiation with low energy levels to enucleated bulbs of rabbits. With an adjusted pressure transducer we examined acoustical transients generated in the area of absorption of the ciliary muscle or the pigmented epithelial layer and measured axial resolution of the method at various distances to the corneoscleral limbus. Results. We detected acoustic transients that allowed rough localization of the target area. A marked change in signal was recorded with increasing level of ciliary destruction. Conclusion. This procedure can serve as an essential tool in the on-line supervision of the coagulation process. The laser parameters can thus be adjusted optimally to the progress of the treatment.

Schlagwörter

    Glaucoma, Laser cyclophotocoagulation, On-line supervision mechanism, Optoacoustics, Pressure transients

ASJC Scopus Sachgebiete

Zitieren

Optoakustische Gewebsdifferenzierung zur Optimierung von Laserzyklophotokoagulation: Transsklerale Detektion laserinduzierter optoakustischer Drucktransienten. / Bruder, I. A.; Büsching, A.; Oberheide, U. et al.
in: OPHTHALMOLOGE, Jahrgang 98, Nr. 3, 03.2001, S. 258-264.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Bruder IA, Büsching A, Oberheide U, Lubatschowski H, Welling H, Ertmer W. Optoakustische Gewebsdifferenzierung zur Optimierung von Laserzyklophotokoagulation: Transsklerale Detektion laserinduzierter optoakustischer Drucktransienten. OPHTHALMOLOGE. 2001 Mär;98(3):258-264. doi: 10.1007/s003470170159
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abstract = "Background. Considerable problems occur in transscleral laser cyclophotocoagulation concerning energy dosage. We investigated the feasibility of localizing the ciliary body by the detection of thermoelastic pressure transients and of supervising on-line the degree of tissue damage during treatment. Method. We used a specially designed handpiece to apply short pulsed laser radiation with low energy levels to enucleated bulbs of rabbits. With an adjusted pressure transducer we examined acoustical transients generated in the area of absorption of the ciliary muscle or the pigmented epithelial layer and measured axial resolution of the method at various distances to the corneoscleral limbus. Results. We detected acoustic transients that allowed rough localization of the target area. A marked change in signal was recorded with increasing level of ciliary destruction. Conclusion. This procedure can serve as an essential tool in the on-line supervision of the coagulation process. The laser parameters can thus be adjusted optimally to the progress of the treatment.",
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Download

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T1 - Optoakustische Gewebsdifferenzierung zur Optimierung von Laserzyklophotokoagulation

T2 - Transsklerale Detektion laserinduzierter optoakustischer Drucktransienten

AU - Bruder, I. A.

AU - Büsching, A.

AU - Oberheide, U.

AU - Lubatschowski, H.

AU - Welling, H.

AU - Ertmer, W.

PY - 2001/3

Y1 - 2001/3

N2 - Background. Considerable problems occur in transscleral laser cyclophotocoagulation concerning energy dosage. We investigated the feasibility of localizing the ciliary body by the detection of thermoelastic pressure transients and of supervising on-line the degree of tissue damage during treatment. Method. We used a specially designed handpiece to apply short pulsed laser radiation with low energy levels to enucleated bulbs of rabbits. With an adjusted pressure transducer we examined acoustical transients generated in the area of absorption of the ciliary muscle or the pigmented epithelial layer and measured axial resolution of the method at various distances to the corneoscleral limbus. Results. We detected acoustic transients that allowed rough localization of the target area. A marked change in signal was recorded with increasing level of ciliary destruction. Conclusion. This procedure can serve as an essential tool in the on-line supervision of the coagulation process. The laser parameters can thus be adjusted optimally to the progress of the treatment.

AB - Background. Considerable problems occur in transscleral laser cyclophotocoagulation concerning energy dosage. We investigated the feasibility of localizing the ciliary body by the detection of thermoelastic pressure transients and of supervising on-line the degree of tissue damage during treatment. Method. We used a specially designed handpiece to apply short pulsed laser radiation with low energy levels to enucleated bulbs of rabbits. With an adjusted pressure transducer we examined acoustical transients generated in the area of absorption of the ciliary muscle or the pigmented epithelial layer and measured axial resolution of the method at various distances to the corneoscleral limbus. Results. We detected acoustic transients that allowed rough localization of the target area. A marked change in signal was recorded with increasing level of ciliary destruction. Conclusion. This procedure can serve as an essential tool in the on-line supervision of the coagulation process. The laser parameters can thus be adjusted optimally to the progress of the treatment.

KW - Glaucoma

KW - Laser cyclophotocoagulation

KW - On-line supervision mechanism

KW - Optoacoustics

KW - Pressure transients

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