Details
| Originalsprache | Englisch |
|---|---|
| Titel des Sammelwerks | XIV Russian-Germany Conference on Biomedical Engineering, RGC 2019 |
| Herausgeber/-innen | A. Yu Gryaznov, N. N. Potrakhov, D. K. Kostrin |
| Herausgeber (Verlag) | American Institute of Physics Inc. |
| Seitenumfang | 4 |
| ISBN (elektronisch) | 9780735418837 |
| Publikationsstatus | Veröffentlicht - 9 Aug. 2019 |
| Veranstaltung | 14th Russian-Germany Conference on Biomedical Engineering, RGC 2019 - St. Petersburg, Russland Dauer: 3 Juli 2019 → 6 Juli 2019 |
Publikationsreihe
| Name | AIP Conference Proceedings |
|---|---|
| Band | 2140 |
| ISSN (Print) | 0094-243X |
| ISSN (elektronisch) | 1551-7616 |
Abstract
Blood glucose level in patients with diabetes mellitus type 1 is controlled by external administration of insulin. Physical activity is a disturbance in blood glucose control, as it influences the glucoregulatory system significantly. In this paper, strategies for improving blood glucose control during physical activity are examined and compared using an extended version of the Sorensen glucoregulatory model. Investigated control strategies for open loop control are a feedforward compensator, which is informed about the intensity of performed activity, and an adaption of insulin infusion rate according to a fixed pattern. Control strategies for closed loop control are a PID controller, a combination of a PID controller and a feedforward compensator and a PID controller, whose setpoint is increased during activity. Results show that best blood glucose control is achieved with strategies including the feedforward compensator due to the achieved reduction of the deviation from the basal value, reduction of time in hypoglycemia and increase in minimal blood glucose level.
ASJC Scopus Sachgebiete
- Physik und Astronomie (insg.)
- Allgemeine Physik und Astronomie
Ziele für nachhaltige Entwicklung
Zitieren
- Standard
- Harvard
- Apa
- Vancouver
- BibTex
- RIS
XIV Russian-Germany Conference on Biomedical Engineering, RGC 2019. Hrsg. / A. Yu Gryaznov; N. N. Potrakhov; D. K. Kostrin. American Institute of Physics Inc., 2019. 020057 (AIP Conference Proceedings; Band 2140).
Publikation: Beitrag in Buch/Bericht/Sammelwerk/Konferenzband › Aufsatz in Konferenzband › Forschung › Peer-Review
}
TY - GEN
T1 - In silico comparison of control strategies of insulin therapy for type 1 diabetes during physical activity using the extended sorensen glucoregulatory model
AU - Romanski, B.
AU - Benner, C.
AU - Glasmacher, Birgit
AU - Leonhardt, S.
AU - Walter, Marian
PY - 2019/8/9
Y1 - 2019/8/9
N2 - Blood glucose level in patients with diabetes mellitus type 1 is controlled by external administration of insulin. Physical activity is a disturbance in blood glucose control, as it influences the glucoregulatory system significantly. In this paper, strategies for improving blood glucose control during physical activity are examined and compared using an extended version of the Sorensen glucoregulatory model. Investigated control strategies for open loop control are a feedforward compensator, which is informed about the intensity of performed activity, and an adaption of insulin infusion rate according to a fixed pattern. Control strategies for closed loop control are a PID controller, a combination of a PID controller and a feedforward compensator and a PID controller, whose setpoint is increased during activity. Results show that best blood glucose control is achieved with strategies including the feedforward compensator due to the achieved reduction of the deviation from the basal value, reduction of time in hypoglycemia and increase in minimal blood glucose level.
AB - Blood glucose level in patients with diabetes mellitus type 1 is controlled by external administration of insulin. Physical activity is a disturbance in blood glucose control, as it influences the glucoregulatory system significantly. In this paper, strategies for improving blood glucose control during physical activity are examined and compared using an extended version of the Sorensen glucoregulatory model. Investigated control strategies for open loop control are a feedforward compensator, which is informed about the intensity of performed activity, and an adaption of insulin infusion rate according to a fixed pattern. Control strategies for closed loop control are a PID controller, a combination of a PID controller and a feedforward compensator and a PID controller, whose setpoint is increased during activity. Results show that best blood glucose control is achieved with strategies including the feedforward compensator due to the achieved reduction of the deviation from the basal value, reduction of time in hypoglycemia and increase in minimal blood glucose level.
UR - http://www.scopus.com/inward/record.url?scp=85071249025&partnerID=8YFLogxK
U2 - 10.1063/1.5121982
DO - 10.1063/1.5121982
M3 - Conference contribution
AN - SCOPUS:85071249025
T3 - AIP Conference Proceedings
BT - XIV Russian-Germany Conference on Biomedical Engineering, RGC 2019
A2 - Gryaznov, A. Yu
A2 - Potrakhov, N. N.
A2 - Kostrin, D. K.
PB - American Institute of Physics Inc.
T2 - 14th Russian-Germany Conference on Biomedical Engineering, RGC 2019
Y2 - 3 July 2019 through 6 July 2019
ER -