Efficient synthesis of novel bis(dihydropyrano[2,3-c]pyrazoles), bis(4Hchromenes) and bis(dihydropyrano[3,2-c]chromenes) with amide functionality

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OriginalspracheEnglisch
Seiten (von - bis)306-324
Seitenumfang19
FachzeitschriftArkivoc
Jahrgang2019
Ausgabenummer6
PublikationsstatusVeröffentlicht - 17 Dez. 2019

Abstract

A synthesis of novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles), bis(4H-chromene-3-carbonitriles) and bis(dihydropyrano[3,2-c]chromenes), which are linked to aliphatic spacers via amide linkages was achieved via multicomponent reactions (MCR) of the appropriate bis-aldehyde with two equivalents of both of malononitrile and 3-methylpyrazol-5-one, dimedone or 4-hydroxycoumarin in a basic solution.

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Efficient synthesis of novel bis(dihydropyrano[2,3-c]pyrazoles), bis(4Hchromenes) and bis(dihydropyrano[3,2-c]chromenes) with amide functionality. / Abdella, Amna M.; Abdelmoniem, Amr M.; Butenschön, Holger et al.
in: Arkivoc, Jahrgang 2019, Nr. 6, 17.12.2019, S. 306-324.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Abdella AM, Abdelmoniem AM, Butenschön H, Abdelhamid IA, Elwahy AHM. Efficient synthesis of novel bis(dihydropyrano[2,3-c]pyrazoles), bis(4Hchromenes) and bis(dihydropyrano[3,2-c]chromenes) with amide functionality. Arkivoc. 2019 Dez 17;2019(6):306-324. doi: 10.24820/ark.5550190.p011.071
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title = "Efficient synthesis of novel bis(dihydropyrano[2,3-c]pyrazoles), bis(4Hchromenes) and bis(dihydropyrano[3,2-c]chromenes) with amide functionality",
abstract = "A synthesis of novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles), bis(4H-chromene-3-carbonitriles) and bis(dihydropyrano[3,2-c]chromenes), which are linked to aliphatic spacers via amide linkages was achieved via multicomponent reactions (MCR) of the appropriate bis-aldehyde with two equivalents of both of malononitrile and 3-methylpyrazol-5-one, dimedone or 4-hydroxycoumarin in a basic solution.",
keywords = "2-c]chromene), 3-c]pyrazole), Amide linkages, Bis(chromene), Bis(pyrano[2, Bis(pyrano[3",
author = "Abdella, {Amna M.} and Abdelmoniem, {Amr M.} and Holger Butensch{\"o}n and Abdelhamid, {Ismail A.} and Elwahy, {Ahmed H.M.}",
note = "Funding information: The authors thank the Alexander von Humboldt Foundation for postdoctoral fellowship. The authors also thank Hannover University for NMR access facilities.",
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T1 - Efficient synthesis of novel bis(dihydropyrano[2,3-c]pyrazoles), bis(4Hchromenes) and bis(dihydropyrano[3,2-c]chromenes) with amide functionality

AU - Abdella, Amna M.

AU - Abdelmoniem, Amr M.

AU - Butenschön, Holger

AU - Abdelhamid, Ismail A.

AU - Elwahy, Ahmed H.M.

N1 - Funding information: The authors thank the Alexander von Humboldt Foundation for postdoctoral fellowship. The authors also thank Hannover University for NMR access facilities.

PY - 2019/12/17

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AB - A synthesis of novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles), bis(4H-chromene-3-carbonitriles) and bis(dihydropyrano[3,2-c]chromenes), which are linked to aliphatic spacers via amide linkages was achieved via multicomponent reactions (MCR) of the appropriate bis-aldehyde with two equivalents of both of malononitrile and 3-methylpyrazol-5-one, dimedone or 4-hydroxycoumarin in a basic solution.

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KW - 3-c]pyrazole)

KW - Amide linkages

KW - Bis(chromene)

KW - Bis(pyrano[2

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DO - 10.24820/ark.5550190.p011.071

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JO - Arkivoc

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